Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland
BACKGROUND Living donor renal transplantation is widely performed in Switzerland with a superior long-term outcome and lower waiting time compared with deceased renal transplantation. However the chances of receiving a living donor kidney transplant are not the same for all transplant ca...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2021-08-01
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| Series: | Swiss Medical Weekly |
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| Online Access: | https://www.smw.ch/index.php/smw/article/view/3047 |
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| author | Rita Achermann Michael Koller Sabina De Geest Karine Hadaya Thomas F. Müller Uyen Huynh-Do Manuel Pascual Jürg Steiger Alexander Kiss Isabelle Binet |
| author_facet | Rita Achermann Michael Koller Sabina De Geest Karine Hadaya Thomas F. Müller Uyen Huynh-Do Manuel Pascual Jürg Steiger Alexander Kiss Isabelle Binet |
| author_sort | Rita Achermann |
| collection | DOAJ |
| description |
BACKGROUND
Living donor renal transplantation is widely performed in Switzerland with a superior long-term outcome and lower waiting time compared with deceased renal transplantation. However the chances of receiving a living donor kidney transplant are not the same for all transplant candidates. The current study aimed to identify psychosocial and demographic characteristics that predict lower access to living kidney donation in Switzerland.
METHODS
The study was a nationwide multicentre study nested within the Swiss Transplant Cohort Study. Pre-transplant demographic, psychosocial and health characteristics of 1126 deceased and 859 living renal transplant recipients were compared using logistic regression analysis.
RESULTS
Transplant candidates with higher age (odds ratio [OR] per 10 years 0.67, 95% confidence interval [CI] 0.60–0.74), lower education (OR 0.46, 95% CI 0.36–0.59), a work capacity of less than 50% (OR 0.48, 95% CI 0.35–0.66), single or formerly married (OR 0.38, 95% CI 0.26–0.53 / OR 0.37, 95% CI 0.26–0.53) or with a higher hospital depression score (OR per 5 points 0.61, 95% CI 0.50–0.74) were less likely to receive an allograft from a living donor. In some regions of Switzerland candidates were more likely to undergo living transplantation than in other regions. No association was found with gender or income.
CONCLUSIONS
Interventions to increase access to kidney transplantation from living donors should target transplant candidates of older age, lower education, lower working capacity and not living in a committed relationship. The observed regional differences suggest that additional determinants of living donation may play a role such as population and health professional attitudes toward living donation.
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| first_indexed | 2024-04-11T04:27:23Z |
| format | Article |
| id | doaj.art-accd59aa146b402694fbf67b31ac83da |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-11T04:27:23Z |
| publishDate | 2021-08-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-accd59aa146b402694fbf67b31ac83da2022-12-29T16:01:26ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972021-08-01151313210.4414/smw.2021.20532Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in SwitzerlandRita Achermann0Michael Koller1Sabina De Geest2Karine Hadaya3Thomas F. Müller4Uyen Huynh-Do5Manuel Pascual6Jürg Steiger7Alexander Kiss8Isabelle Binet9Transplantation Immunology and Nephrology, University Hospital Basel, SwitzerlandTransplantation Immunology and Nephrology, University Hospital Basel, SwitzerlandInstitute of Nursing Science, University of Basel, Switzerland; Department of Public Health and Primary Care, Academic Centre for Nursing and Midwifery, KU Leuven, BelgiumDivision of Transplantation and Nephrology, University of Geneva Hospitals, SwitzerlandDivision of Nephrology, University Hospital Zurich, SwitzerlandDivision of Nephrology and Hypertension, University Hospital Bern Inselspital, Bern, SwitzerlandTransplantation Centre, Centre Hospitalier Universitaire Vaudois and University of Lausanne, SwitzerlandTransplantation Immunology and Nephrology, University Hospital Basel, SwitzerlandDepartment of Psychosomatic Medicine, University Hospital Basel, SwitzerlandNephrologie/Transplantationsmedizin, Kantonsspital St. Gallen, Switzerland BACKGROUND Living donor renal transplantation is widely performed in Switzerland with a superior long-term outcome and lower waiting time compared with deceased renal transplantation. However the chances of receiving a living donor kidney transplant are not the same for all transplant candidates. The current study aimed to identify psychosocial and demographic characteristics that predict lower access to living kidney donation in Switzerland. METHODS The study was a nationwide multicentre study nested within the Swiss Transplant Cohort Study. Pre-transplant demographic, psychosocial and health characteristics of 1126 deceased and 859 living renal transplant recipients were compared using logistic regression analysis. RESULTS Transplant candidates with higher age (odds ratio [OR] per 10 years 0.67, 95% confidence interval [CI] 0.60–0.74), lower education (OR 0.46, 95% CI 0.36–0.59), a work capacity of less than 50% (OR 0.48, 95% CI 0.35–0.66), single or formerly married (OR 0.38, 95% CI 0.26–0.53 / OR 0.37, 95% CI 0.26–0.53) or with a higher hospital depression score (OR per 5 points 0.61, 95% CI 0.50–0.74) were less likely to receive an allograft from a living donor. In some regions of Switzerland candidates were more likely to undergo living transplantation than in other regions. No association was found with gender or income. CONCLUSIONS Interventions to increase access to kidney transplantation from living donors should target transplant candidates of older age, lower education, lower working capacity and not living in a committed relationship. The observed regional differences suggest that additional determinants of living donation may play a role such as population and health professional attitudes toward living donation. https://www.smw.ch/index.php/smw/article/view/3047kidney transplantationliving donation recipientssocio-demographic characteristics of kidney transplant recipients |
| spellingShingle | Rita Achermann Michael Koller Sabina De Geest Karine Hadaya Thomas F. Müller Uyen Huynh-Do Manuel Pascual Jürg Steiger Alexander Kiss Isabelle Binet Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland Swiss Medical Weekly kidney transplantation living donation recipients socio-demographic characteristics of kidney transplant recipients |
| title | Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland |
| title_full | Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland |
| title_fullStr | Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland |
| title_full_unstemmed | Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland |
| title_short | Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland |
| title_sort | demographic psychosocial and health disparities between living and deceased renal allograft recipients in switzerland |
| topic | kidney transplantation living donation recipients socio-demographic characteristics of kidney transplant recipients |
| url | https://www.smw.ch/index.php/smw/article/view/3047 |
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