S‐allyl‐L‐cysteine protects hepatocytes from indomethacin‐induced apoptosis by attenuating endoplasmic reticulum stress

S‐allyl‐L‐cysteine protects hepatocytes from indomethacin‐induced apoptosis by attenuating endoplasmic reticulum stress

Drug‐induced liver injury (DILI) can lead to acute liver failure, a lethal condition which may require liver transplantation. Hepatotoxicity associated with nonsteroidal anti‐inflammatory drugs (NSAIDs) accounts for ~ 10% of all DILI. In the current study, we determined whether indomethacin, one of...

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Bibliographic Details
Main Authors: Peng Chen, Chen Chen, Mingdao Hu, Rui Cui, Feng Liu, Henghai Yu, Yuling Ren
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:FEBS Open Bio
Subjects:
apoptosis
endoplasmic reticulum stress
hepatocyte
indomethacin
S‐allyl‐l‐cysteine
Online Access:https://doi.org/10.1002/2211-5463.12945

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