Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine

Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine

Summary: Matching the treatment to an individual patient’s tumor state can increase therapeutic efficacy and reduce tumor recurrence. Circulating tumor cells (CTCs) derived from solid tumors are promising subjects for theragnostic analysis. To analyze how CTCs represent tumor states, we established...

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Bibliographic Details
Main Authors: Jia-Yang Chen, Hsu-Huan Chou, Syer Choon Lim, Yen-Jang Huang, Kuan-Chen Lai, Chin-Lin Guo, Chien-Yi Tung, Chung-Tsai Su, Jocelyn Wang, Edward Liu, Hsiao-Fen Han, Po-Ying Yeh, Chun-Mei Hu, Alexander R. Dunn, Curtis W. Frank, Yi-Chun Wu, Muh-Hwa Yang, Ying-Chih Chang
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:iScience
Subjects:
Precision medicine
Cancer
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222013530

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