Sleep loss potentiates Th17‐cell pathogenicity and promotes autoimmune uveitis

Sleep loss potentiates Th17‐cell pathogenicity and promotes autoimmune uveitis

Abstract Background Sleep loss (SL) is a health issue associated with the higher risk of autoimmune and inflammatory disorders. However, the connection between SL, the immune system, and autoimmune diseases remains unknown. Methods We conducted mass cytometry, single‐cell RNA sequencing, and flow cy...

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Bibliographic Details
Main Authors: Xiuxing Liu, Yuhan Su, Zhaohao Huang, Jianjie Lv, Chenyang Gu, Zhuang Li, Tianyu Tao, Yidan Liu, Qi Jiang, Runping Duan, Binyao Chen, Rong Ju, Xianggui Wang, Yingfeng Zheng, Wenru Su
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Clinical and Translational Medicine
Subjects:
autoimmune disease
GM‐CSF
mass cytometry
myeloid cells
single‐cell RNA sequencing
sleep loss
Online Access:https://doi.org/10.1002/ctm2.1250

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