Adipocyte‐Specific Enhancement of Angiotensin II Type 1 Receptor‐Associated Protein Ameliorates Diet‐Induced Visceral Obesity and Insulin Resistance

Adipocyte‐Specific Enhancement of Angiotensin II Type 1 Receptor‐Associated Protein Ameliorates Diet‐Induced Visceral Obesity and Insulin Resistance

Background The renin–angiotensin system has a pivotal role in the pathophysiology of visceral obesity. Angiotensin II type 1 receptor (AT1R) is a major player in the signal transduction of the renin–angiotensin system, and the overactivation of this signaling contributes to the progression of viscer...

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Bibliographic Details
Main Authors: Kengo Azushima, Kohji Ohki, Hiromichi Wakui, Kazushi Uneda, Sona Haku, Ryu Kobayashi, Kotaro Haruhara, Sho Kinguchi, Miyuki Matsuda, Akinobu Maeda, Yoshiyuki Toya, Akio Yamashita, Satoshi Umemura, Kouichi Tamura
Format: Article
Language:English
Published: Wiley 2017-03-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
adipocyte
insulin resistance
obesity
receptor
renin–angiotensin system
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004488

Internet

https://www.ahajournals.org/doi/10.1161/JAHA.116.004488

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