Synthetic cinnamates as potential antimicrobial agents
This study deals with synthesis of methyl cinnamate, butyl cinnamate, and p-methoxy methyl cinnamate and testing of their in vitro antimicrobial activity. Antimicrobial activity was examined towards 29 microorganisms using microdilution method. It is shown that antimicrobial activity of met...
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| Format: | Article |
| Language: | English |
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Association of Chemical Engineers of Serbia
2015-01-01
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| Series: | Hemijska Industrija |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0367-598X/2015/0367-598X1400014S.pdf |
| _version_ | 1819058562365652992 |
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| author | Stefanović Olgica D. Radojević Ivana D. Čomić Ljiljana R. |
| author_facet | Stefanović Olgica D. Radojević Ivana D. Čomić Ljiljana R. |
| author_sort | Stefanović Olgica D. |
| collection | DOAJ |
| description | This study deals with synthesis of methyl cinnamate, butyl cinnamate, and
p-methoxy methyl cinnamate and testing of their in vitro antimicrobial
activity. Antimicrobial activity was examined towards 29 microorganisms using
microdilution method. It is shown that antimicrobial activity of methyl
cinnamate and p-methoxy methyl cinnamate was better than that of butyl
cinnamate. Sarcina lutea, Bacillus subtilis ATCC 6633, B. subtilis and B.
subtilis IP 5832 (probiotic) were the most sensitive bacteria. It is
established that p-methoxy methyl cinnamate can be a new, potential
anti-Staphylococcus aureus agent with minimum inhibitory concentration of
62.5 μg/ml. Methyl cinnamate and p-methoxy methyl cinnamate inhibited the
growth of Aspergillus restrictus, A. flavus and A. fumigatus in the
concentration range from 62.5 μg/ml to 250 μg/ml. |
| first_indexed | 2024-12-21T13:57:10Z |
| format | Article |
| id | doaj.art-ace12c892ff14188bb7990c1f852e9a6 |
| institution | Directory Open Access Journal |
| issn | 0367-598X 2217-7426 |
| language | English |
| last_indexed | 2024-12-21T13:57:10Z |
| publishDate | 2015-01-01 |
| publisher | Association of Chemical Engineers of Serbia |
| record_format | Article |
| series | Hemijska Industrija |
| spelling | doaj.art-ace12c892ff14188bb7990c1f852e9a62022-12-21T19:01:31ZengAssociation of Chemical Engineers of SerbiaHemijska Industrija0367-598X2217-74262015-01-01691374210.2298/HEMIND130928014S0367-598X1400014SSynthetic cinnamates as potential antimicrobial agentsStefanović Olgica D.0Radojević Ivana D.1Čomić Ljiljana R.2Faculty of Science, Department of Biology and Ecology, KragujevacFaculty of Science, Department of Biology and Ecology, KragujevacFaculty of Science, Department of Biology and Ecology, KragujevacThis study deals with synthesis of methyl cinnamate, butyl cinnamate, and p-methoxy methyl cinnamate and testing of their in vitro antimicrobial activity. Antimicrobial activity was examined towards 29 microorganisms using microdilution method. It is shown that antimicrobial activity of methyl cinnamate and p-methoxy methyl cinnamate was better than that of butyl cinnamate. Sarcina lutea, Bacillus subtilis ATCC 6633, B. subtilis and B. subtilis IP 5832 (probiotic) were the most sensitive bacteria. It is established that p-methoxy methyl cinnamate can be a new, potential anti-Staphylococcus aureus agent with minimum inhibitory concentration of 62.5 μg/ml. Methyl cinnamate and p-methoxy methyl cinnamate inhibited the growth of Aspergillus restrictus, A. flavus and A. fumigatus in the concentration range from 62.5 μg/ml to 250 μg/ml.http://www.doiserbia.nb.rs/img/doi/0367-598X/2015/0367-598X1400014S.pdfMethyl cinnamatebutyl cinnamatep-methoxy methyl cinnamateantimicrobial activitybacteriafungi |
| spellingShingle | Stefanović Olgica D. Radojević Ivana D. Čomić Ljiljana R. Synthetic cinnamates as potential antimicrobial agents Hemijska Industrija Methyl cinnamate butyl cinnamate p-methoxy methyl cinnamate antimicrobial activity bacteria fungi |
| title | Synthetic cinnamates as potential antimicrobial agents |
| title_full | Synthetic cinnamates as potential antimicrobial agents |
| title_fullStr | Synthetic cinnamates as potential antimicrobial agents |
| title_full_unstemmed | Synthetic cinnamates as potential antimicrobial agents |
| title_short | Synthetic cinnamates as potential antimicrobial agents |
| title_sort | synthetic cinnamates as potential antimicrobial agents |
| topic | Methyl cinnamate butyl cinnamate p-methoxy methyl cinnamate antimicrobial activity bacteria fungi |
| url | http://www.doiserbia.nb.rs/img/doi/0367-598X/2015/0367-598X1400014S.pdf |
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