Neoadjuvant/Perioperative Treatment Affects Spatial Distribution and Densities of Tumor Associated Neutrophils and CD8+ Lymphocytes in Gastric Cancer

Neoadjuvant/Perioperative Treatment Affects Spatial Distribution and Densities of Tumor Associated Neutrophils and CD8+ Lymphocytes in Gastric Cancer

Tumor associated neutrophils (TANs) and cytotoxic T cells (CTLs) are part of the tumor microenvironment of gastric cancer (GC). We explored their tumor biological significance in neoadjuvantly/perioperatively treated GC. Immunostaining was performed on whole tissue sections of 173 GCs, using antibod...

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Bibliographic Details
Main Authors: Anne Hoffmann, Hans-Michael Behrens, Steffen Heckl, Sandra Krüger, Thomas Becker, Christoph Röcken
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Journal of Personalized Medicine
Subjects:
gastric cancer
tumor associated neutrophils
cytotoxic T cells
Online Access:https://www.mdpi.com/2075-4426/11/11/1184

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