Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor
Refined palm oil products may contain a harmful substance called as 3-monochloropropane-1,2-diol (3-MCPD), which can potentially be carcinogenic if consumed in excess. The determination of 3-MCPD depends on the sophisticated machine and highly skilled technicians but it is time-consuming. A simple m...
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| Format: | Article |
| Language: | English |
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Komunitas Ilmuwan dan Profesional Muslim Indonesia
2023-07-01
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| Series: | Communications in Science and Technology |
| Subjects: | |
| Online Access: | https://cst.kipmi.or.id/journal/article/view/1167 |
| _version_ | 1797783466301980672 |
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| author | Yora Faramitha Fadhlurrahman Rafi Barori Firda Dimawarnita Siswanto Havid Aqoma Adam F Nugraha Alfian Ferdiansyah |
| author_facet | Yora Faramitha Fadhlurrahman Rafi Barori Firda Dimawarnita Siswanto Havid Aqoma Adam F Nugraha Alfian Ferdiansyah |
| author_sort | Yora Faramitha |
| collection | DOAJ |
| description | Refined palm oil products may contain a harmful substance called as 3-monochloropropane-1,2-diol (3-MCPD), which can potentially be carcinogenic if consumed in excess. The determination of 3-MCPD depends on the sophisticated machine and highly skilled technicians but it is time-consuming. A simple method that proposes rapid detection remains a challenge. Hence, this research aims to develop a colorimetric-based rapid detection sensor using gold nanoparticles functionalized with a ligand, glutathione (GSH) to be bound to 3-MCPD. Varied concentrations of GSH were evaluated to obtain stable GSH-AuNPs. The characterization results showed that the composition of the stable GSH-AuNPs has been achieved by 250 µL of 0.02 M GSH addition. A stable GSH-AuNPs was ruby red with surface plasmon resonance (SPR) band at 520 nm and an average nanoparticle size of 30 nm. The indication for detection of 3-MCPD was marked by the decrease in the absorbance intensity. Thus, GSH-AuNPs have potential to be developed for the 3-MCPD sensor application. |
| first_indexed | 2024-03-13T00:26:25Z |
| format | Article |
| id | doaj.art-ace35b35096144ef9b8b403ea0eebebd |
| institution | Directory Open Access Journal |
| issn | 2502-9258 2502-9266 |
| language | English |
| last_indexed | 2024-03-13T00:26:25Z |
| publishDate | 2023-07-01 |
| publisher | Komunitas Ilmuwan dan Profesional Muslim Indonesia |
| record_format | Article |
| series | Communications in Science and Technology |
| spelling | doaj.art-ace35b35096144ef9b8b403ea0eebebd2023-07-11T06:26:50ZengKomunitas Ilmuwan dan Profesional Muslim IndonesiaCommunications in Science and Technology2502-92582502-92662023-07-0181828610.21924/cst.8.1.2023.11671167Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensorYora Faramitha0Fadhlurrahman Rafi Barori1Firda Dimawarnita2Siswanto3Havid Aqoma4Adam F Nugraha5Alfian Ferdiansyah6Indonesian Oil Palm Research Institute–Bogor Unit, Bogor 16128, IndonesiaDepartment of Metallurgical and Materials Engineering, Faculty of Engineering, Universitas Indonesia, Depok 16424, IndonesiaIndonesian Oil Palm Research Institute–Bogor Unit, Bogor 16128, IndonesiaIndonesian Oil Palm Research Institute–Bogor Unit, Bogor 16128, IndonesiaKelip-kelip!, Center of Excellence for Light Enabling Technologies, School of Energy and Chemical Engineering, Xiamen University Malaysia, Selangor 43900, MalaysiaDepartment of Metallurgical and Materials Engineering, Faculty of Engineering, Universitas Indonesia, Depok 16424, IndonesiaDepartment of Metallurgical and Materials Engineering, Faculty of Engineering, Universitas Indonesia, Depok 16424, IndonesiaRefined palm oil products may contain a harmful substance called as 3-monochloropropane-1,2-diol (3-MCPD), which can potentially be carcinogenic if consumed in excess. The determination of 3-MCPD depends on the sophisticated machine and highly skilled technicians but it is time-consuming. A simple method that proposes rapid detection remains a challenge. Hence, this research aims to develop a colorimetric-based rapid detection sensor using gold nanoparticles functionalized with a ligand, glutathione (GSH) to be bound to 3-MCPD. Varied concentrations of GSH were evaluated to obtain stable GSH-AuNPs. The characterization results showed that the composition of the stable GSH-AuNPs has been achieved by 250 µL of 0.02 M GSH addition. A stable GSH-AuNPs was ruby red with surface plasmon resonance (SPR) band at 520 nm and an average nanoparticle size of 30 nm. The indication for detection of 3-MCPD was marked by the decrease in the absorbance intensity. Thus, GSH-AuNPs have potential to be developed for the 3-MCPD sensor application.https://cst.kipmi.or.id/journal/article/view/1167aunpsligand3-mcpd |
| spellingShingle | Yora Faramitha Fadhlurrahman Rafi Barori Firda Dimawarnita Siswanto Havid Aqoma Adam F Nugraha Alfian Ferdiansyah Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor Communications in Science and Technology aunps ligand 3-mcpd |
| title | Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor |
| title_full | Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor |
| title_fullStr | Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor |
| title_full_unstemmed | Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor |
| title_short | Fabrication of glutathione-modified gold nanoparticles as 3-chloropropane-1,2-diol sensor |
| title_sort | fabrication of glutathione modified gold nanoparticles as 3 chloropropane 1 2 diol sensor |
| topic | aunps ligand 3-mcpd |
| url | https://cst.kipmi.or.id/journal/article/view/1167 |
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