A Rapid and Sensitive LC−MS/MS Method for the Quantitation of Physalin A with Special Consideration to Chemical Stability in Rat Plasma: Application to a Pharmacokinetic Study

A Rapid and Sensitive LC−MS/MS Method for the Quantitation of Physalin A with Special Consideration to Chemical Stability in Rat Plasma: Application to a Pharmacokinetic Study

Physalin A is a promising natural product with excellent anti-inflammatory and anti-tumor activities. However, the pharmacokinetic profile of physalin A is still unclear. In this study, a rapid and sensitive analytical method based on LC–MS/MS for the quantitation of physalin A in rat plasma with sp...

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Bibliographic Details
Main Authors: Yang Li, Na Zhao, Tingting Zhang, Xinchi Feng
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
physalin A
LC–MS/MS
stability
pharmacokinetics
Online Access:https://www.mdpi.com/1420-3049/27/21/7272

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