Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

Prognostic Significance of Interferon-γ and Its Signaling Pathway in Early Breast Cancer Depends on the Molecular Subtypes

Interferons are crucial for adaptive immunity and play an important role in the immune landscape of breast cancer. Using microarray-based gene expression analysis, we examined the subtype-specific prognostic significance of interferon-γ (IFN-γ) as a single gene as well as an IFN-γ signature covering...

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Bibliographic Details
Main Authors: Anne-Sophie Heimes, Franziska Härtner, Katrin Almstedt, Slavomir Krajnak, Antje Lebrecht, Marco J. Battista, Karolina Edlund, Walburgis Brenner, Annette Hasenburg, Ugur Sahin, Mathias Gehrmann, Jan G. Hengstler, Marcus Schmidt
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
interferon
breast cancer
prognosis
molecular subtypes
Online Access:https://www.mdpi.com/1422-0067/21/19/7178

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