The Glucose-Regulated MiR-483-3p Influences Key Signaling Pathways in Cancer

The hsa-mir-483 gene, located within the IGF2 locus, transcribes for two mature microRNAs, miR-483-5p and miR-483-3p. This gene, whose regulation is mediated by the the CTNNB1/USF1 complex, shows an independent expression from its host gene IGF2. The miR-483-3p affects the Wnt/β-catenin, th...

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Bibliographic Details
Main Authors: Felice Pepe, Rosa Visone, Angelo Veronese
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/6/181