Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo

Pericardial effusion is an accumulation of fluid in the pericardial sac. It is caused by exudative or transudative collections. Large effusions can lead to a life-threatening condition called tamponade if not intervened properly. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis are life...

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Main Authors: Iragavarapu Tammiraju, B Srinivas, K Nirupama, K Pruthvi Naresh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Journal of Indian College of Cardiology
Subjects:
Online Access:http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=82;epage=85;aulast=Tammiraju
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author Iragavarapu Tammiraju
B Srinivas
K Nirupama
K Pruthvi Naresh
author_facet Iragavarapu Tammiraju
B Srinivas
K Nirupama
K Pruthvi Naresh
author_sort Iragavarapu Tammiraju
collection DOAJ
description Pericardial effusion is an accumulation of fluid in the pericardial sac. It is caused by exudative or transudative collections. Large effusions can lead to a life-threatening condition called tamponade if not intervened properly. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis are life-threatening cutaneous drug reactions in which the epidermis is separated from the dermis. The diagnosis mainly relies on the clinical signs and histopathology of skin lesions. Immunological mechanisms, reactive drug metabolites, or interactions between these two are proposed. Here, we report a case of recurrent cardiac tamponade with SJS secondary to empirical antituberculous therapy.
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spelling doaj.art-acedc04ba69b4ccdad5036cbcfeab9202024-02-07T12:55:24ZengWolters Kluwer Medknow PublicationsJournal of Indian College of Cardiology1561-88112213-36152021-01-01112828510.4103/JICC.JICC_20_20Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly comboIragavarapu TammirajuB SrinivasK NirupamaK Pruthvi NareshPericardial effusion is an accumulation of fluid in the pericardial sac. It is caused by exudative or transudative collections. Large effusions can lead to a life-threatening condition called tamponade if not intervened properly. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis are life-threatening cutaneous drug reactions in which the epidermis is separated from the dermis. The diagnosis mainly relies on the clinical signs and histopathology of skin lesions. Immunological mechanisms, reactive drug metabolites, or interactions between these two are proposed. Here, we report a case of recurrent cardiac tamponade with SJS secondary to empirical antituberculous therapy.http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=82;epage=85;aulast=Tammirajuempirical drugsrecurrent effusionstevens–johnson
spellingShingle Iragavarapu Tammiraju
B Srinivas
K Nirupama
K Pruthvi Naresh
Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
Journal of Indian College of Cardiology
empirical drugs
recurrent effusion
stevens–johnson
title Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
title_full Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
title_fullStr Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
title_full_unstemmed Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
title_short Recurrent cardiac tamponade with stevens–Johnson's syndrome – A rare deadly combo
title_sort recurrent cardiac tamponade with stevens johnson s syndrome a rare deadly combo
topic empirical drugs
recurrent effusion
stevens–johnson
url http://www.joicc.org/article.asp?issn=1561-8811;year=2021;volume=11;issue=2;spage=82;epage=85;aulast=Tammiraju
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AT bsrinivas recurrentcardiactamponadewithstevensjohnsonssyndromeararedeadlycombo
AT knirupama recurrentcardiactamponadewithstevensjohnsonssyndromeararedeadlycombo
AT kpruthvinaresh recurrentcardiactamponadewithstevensjohnsonssyndromeararedeadlycombo