Human mortality at extreme age

We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads to the conclusion that constant force of mor...

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Main Authors: Léo R. Belzile, Anthony C. Davison, Holger Rootzén, Dmitrii Zholud
Format: Article
Language:English
Published: The Royal Society 2021-09-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.202097
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author Léo R. Belzile
Anthony C. Davison
Holger Rootzén
Dmitrii Zholud
author_facet Léo R. Belzile
Anthony C. Davison
Holger Rootzén
Dmitrii Zholud
author_sort Léo R. Belzile
collection DOAJ
description We use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads to the conclusion that constant force of mortality beyond 108 years describes the data well and there is no evidence of differences between countries and cohorts. These findings are consistent with use of a Gompertz model and with previous analysis of the International Database on Longevity and suggest that any physical upper bound for the human lifespan is so large that it is unlikely to be approached. Power calculations make it implausible that there is an upper bound below 130 years. There is no evidence of differences in survival between women and men after age 108 in the Italian data and the International Database on Longevity, but survival is lower for men in the French data.
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spelling doaj.art-acef4cd259d64c169bd3ec3b10c987e22022-12-21T19:58:30ZengThe Royal SocietyRoyal Society Open Science2054-57032021-09-018910.1098/rsos.202097Human mortality at extreme ageLéo R. Belzile0Anthony C. Davison1Holger Rootzén2Dmitrii Zholud3Department of Decision Sciences, HEC Montréal, 3000, chemin de la Côte-Sainte-Catherine, Montréal, Quebec, Canada H3T 2A7Institute of Mathematics, École polytechnique fédérale de Lausanne, Station 8, Lausanne 1015, SwitzerlandDepartment of Mathematical Sciences, Chalmers and Gothenburg University, Chalmers Tvärgata 3, Göteborg 41296, SwedenDepartment of Mathematical Sciences, Chalmers and Gothenburg University, Chalmers Tvärgata 3, Göteborg 41296, SwedenWe use a combination of extreme value statistics, survival analysis and computer-intensive methods to analyse the mortality of Italian and French semi-supercentenarians. After accounting for the effects of the sampling frame, extreme-value modelling leads to the conclusion that constant force of mortality beyond 108 years describes the data well and there is no evidence of differences between countries and cohorts. These findings are consistent with use of a Gompertz model and with previous analysis of the International Database on Longevity and suggest that any physical upper bound for the human lifespan is so large that it is unlikely to be approached. Power calculations make it implausible that there is an upper bound below 130 years. There is no evidence of differences in survival between women and men after age 108 in the Italian data and the International Database on Longevity, but survival is lower for men in the French data.https://royalsocietypublishing.org/doi/10.1098/rsos.202097exponential hazardextreme value theorysemi-supercentenarian
spellingShingle Léo R. Belzile
Anthony C. Davison
Holger Rootzén
Dmitrii Zholud
Human mortality at extreme age
Royal Society Open Science
exponential hazard
extreme value theory
semi-supercentenarian
title Human mortality at extreme age
title_full Human mortality at extreme age
title_fullStr Human mortality at extreme age
title_full_unstemmed Human mortality at extreme age
title_short Human mortality at extreme age
title_sort human mortality at extreme age
topic exponential hazard
extreme value theory
semi-supercentenarian
url https://royalsocietypublishing.org/doi/10.1098/rsos.202097
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AT holgerrootzen humanmortalityatextremeage
AT dmitriizholud humanmortalityatextremeage