Unveiling Gene Interactions in Alzheimer’s Disease by Integrating Genetic and Epigenetic Data with a Network-Based Approach

Alzheimer’s Disease (AD) is a complex disease and the leading cause of dementia in older people. We aimed to uncover aspects of AD’s pathogenesis that may contribute to drug repurposing efforts by integrating DNA methylation and genetic data. Implementing the network-based tool, a dense module searc...

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Autori principali: Keith L. Sanders, Astrid M. Manuel, Andi Liu, Boyan Leng, Xiangning Chen, Zhongming Zhao
Natura: Articolo
Lingua:English
Pubblicazione: MDPI AG 2024-04-01
Serie:Epigenomes
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Accesso online:https://www.mdpi.com/2075-4655/8/2/14