Unveiling Gene Interactions in Alzheimer’s Disease by Integrating Genetic and Epigenetic Data with a Network-Based Approach

Unveiling Gene Interactions in Alzheimer’s Disease by Integrating Genetic and Epigenetic Data with a Network-Based Approach

Alzheimer’s Disease (AD) is a complex disease and the leading cause of dementia in older people. We aimed to uncover aspects of AD’s pathogenesis that may contribute to drug repurposing efforts by integrating DNA methylation and genetic data. Implementing the network-based tool, a dense module searc...

詳細記述

書誌詳細
主要な著者: Keith L. Sanders, Astrid M. Manuel, Andi Liu, Boyan Leng, Xiangning Chen, Zhongming Zhao
フォーマット: 論文
言語:English
出版事項: MDPI AG 2024-04-01
シリーズ:Epigenomes
主題:
epigenetics
DNA methylation
genome-wide association studies (GWAS)
protein–protein interaction
network analysis
オンライン･アクセス:https://www.mdpi.com/2075-4655/8/2/14

インターネット

https://www.mdpi.com/2075-4655/8/2/14

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