The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective
Abstract Healthy lungs were long thought of as sterile, with presence of bacteria identified by culture representing contamination. Recent advances in metagenomics have refuted this belief by detecting rich, diverse, and complex microbial communities in the healthy lower airways of many species, alb...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-09-01
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| Series: | Journal of Veterinary Internal Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/jvim.16824 |
| _version_ | 1797729049162809344 |
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| author | Aida I. Vientós‐Plotts Aaron C. Ericsson Carol R. Reinero |
| author_facet | Aida I. Vientós‐Plotts Aaron C. Ericsson Carol R. Reinero |
| author_sort | Aida I. Vientós‐Plotts |
| collection | DOAJ |
| description | Abstract Healthy lungs were long thought of as sterile, with presence of bacteria identified by culture representing contamination. Recent advances in metagenomics have refuted this belief by detecting rich, diverse, and complex microbial communities in the healthy lower airways of many species, albeit at low concentrations. Although research has only begun to investigate causality and potential mechanisms, alterations in these microbial communities (known as dysbiosis) have been described in association with inflammatory, infectious, and neoplastic respiratory diseases in humans. Similar studies in dogs and cats are scarce. The microbial communities in the respiratory tract are linked to distant microbial communities such as in the gut (ie, the gut‐lung axis), allowing interplay of microbes and microbial products in health and disease. This review summarizes considerations for studying local microbial communities, key features of the respiratory microbiota and its role in the gut‐lung axis, current understanding of the healthy respiratory microbiota, and examples of dysbiosis in selected respiratory diseases of dogs and cats. |
| first_indexed | 2024-03-12T11:23:21Z |
| format | Article |
| id | doaj.art-acf2356e3a7a493b885c7194ae04c52e |
| institution | Directory Open Access Journal |
| issn | 0891-6640 1939-1676 |
| language | English |
| last_indexed | 2024-03-12T11:23:21Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Veterinary Internal Medicine |
| spelling | doaj.art-acf2356e3a7a493b885c7194ae04c52e2023-09-01T14:18:40ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762023-09-013751641165510.1111/jvim.16824The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspectiveAida I. Vientós‐Plotts0Aaron C. Ericsson1Carol R. Reinero2College of Veterinary Medicine University of Missouri Columbia Missouri USACollege of Veterinary Medicine University of Missouri Columbia Missouri USACollege of Veterinary Medicine University of Missouri Columbia Missouri USAAbstract Healthy lungs were long thought of as sterile, with presence of bacteria identified by culture representing contamination. Recent advances in metagenomics have refuted this belief by detecting rich, diverse, and complex microbial communities in the healthy lower airways of many species, albeit at low concentrations. Although research has only begun to investigate causality and potential mechanisms, alterations in these microbial communities (known as dysbiosis) have been described in association with inflammatory, infectious, and neoplastic respiratory diseases in humans. Similar studies in dogs and cats are scarce. The microbial communities in the respiratory tract are linked to distant microbial communities such as in the gut (ie, the gut‐lung axis), allowing interplay of microbes and microbial products in health and disease. This review summarizes considerations for studying local microbial communities, key features of the respiratory microbiota and its role in the gut‐lung axis, current understanding of the healthy respiratory microbiota, and examples of dysbiosis in selected respiratory diseases of dogs and cats.https://doi.org/10.1111/jvim.16824asthmalungmicrobiomenasalpneumonia |
| spellingShingle | Aida I. Vientós‐Plotts Aaron C. Ericsson Carol R. Reinero The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective Journal of Veterinary Internal Medicine asthma lung microbiome nasal pneumonia |
| title | The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective |
| title_full | The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective |
| title_fullStr | The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective |
| title_full_unstemmed | The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective |
| title_short | The respiratory microbiota and its impact on health and disease in dogs and cats: A One Health perspective |
| title_sort | respiratory microbiota and its impact on health and disease in dogs and cats a one health perspective |
| topic | asthma lung microbiome nasal pneumonia |
| url | https://doi.org/10.1111/jvim.16824 |
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