Electrically conductive “SMART” hydrogels for on-demand drug delivery
In the current transformative era of biomedicine, hydrogels have established their presence in biomaterials due to their superior biocompatibility, tuneability and resemblance with native tissue. However, hydrogels typically exhibit poor conductivity due to their hydrophilic polymer structure. Elect...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Asian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1818087624001247 |
| _version_ | 1826538960625598464 |
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| author | Soumajyoti Ghosh Nikhil Kumar Santanu Chattopadhyay |
| author_facet | Soumajyoti Ghosh Nikhil Kumar Santanu Chattopadhyay |
| author_sort | Soumajyoti Ghosh |
| collection | DOAJ |
| description | In the current transformative era of biomedicine, hydrogels have established their presence in biomaterials due to their superior biocompatibility, tuneability and resemblance with native tissue. However, hydrogels typically exhibit poor conductivity due to their hydrophilic polymer structure. Electrical conductivity provides an important enhancement to the properties of hydrogel-based systems in various biomedical applications such as drug delivery and tissue engineering. Consequently, researchers are developing combinatorial strategies to develop electrically responsive “SMART” systems to improve the therapeutic efficacy of biomolecules. Electrically conductive hydrogels have been explored for various drug delivery applications, enabling higher loading of therapeutic cargo with on-demand delivery. This review emphasizes the properties, mechanisms, fabrication techniques and recent advancements of electrically responsive “SMART” systems aiding on-site drug delivery applications. Additionally, it covers prospects for the successful translation of these systems into clinical research. |
| first_indexed | 2025-02-16T17:02:40Z |
| format | Article |
| id | doaj.art-acf235c0cba140e5a0d23a1f3aefeb1c |
| institution | Directory Open Access Journal |
| issn | 1818-0876 |
| language | English |
| last_indexed | 2025-03-14T03:34:54Z |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-acf235c0cba140e5a0d23a1f3aefeb1c2025-03-09T05:13:52ZengElsevierAsian Journal of Pharmaceutical Sciences1818-08762025-02-01201101007Electrically conductive “SMART” hydrogels for on-demand drug deliverySoumajyoti Ghosh0Nikhil Kumar1Santanu Chattopadhyay2Rubber Technology Centre, Indian Institute of Technology, Kharagpur 721302, IndiaAdvanced Technology Development Centre, Indian Institute of Technology, Kharagpur 721302, IndiaRubber Technology Centre, Indian Institute of Technology, Kharagpur 721302, India; Corresponding author.In the current transformative era of biomedicine, hydrogels have established their presence in biomaterials due to their superior biocompatibility, tuneability and resemblance with native tissue. However, hydrogels typically exhibit poor conductivity due to their hydrophilic polymer structure. Electrical conductivity provides an important enhancement to the properties of hydrogel-based systems in various biomedical applications such as drug delivery and tissue engineering. Consequently, researchers are developing combinatorial strategies to develop electrically responsive “SMART” systems to improve the therapeutic efficacy of biomolecules. Electrically conductive hydrogels have been explored for various drug delivery applications, enabling higher loading of therapeutic cargo with on-demand delivery. This review emphasizes the properties, mechanisms, fabrication techniques and recent advancements of electrically responsive “SMART” systems aiding on-site drug delivery applications. Additionally, it covers prospects for the successful translation of these systems into clinical research.http://www.sciencedirect.com/science/article/pii/S1818087624001247HydrogelsConductive polymersElectrically conductive hydrogelsOn-demand drug delivery |
| spellingShingle | Soumajyoti Ghosh Nikhil Kumar Santanu Chattopadhyay Electrically conductive “SMART” hydrogels for on-demand drug delivery Asian Journal of Pharmaceutical Sciences Hydrogels Conductive polymers Electrically conductive hydrogels On-demand drug delivery |
| title | Electrically conductive “SMART” hydrogels for on-demand drug delivery |
| title_full | Electrically conductive “SMART” hydrogels for on-demand drug delivery |
| title_fullStr | Electrically conductive “SMART” hydrogels for on-demand drug delivery |
| title_full_unstemmed | Electrically conductive “SMART” hydrogels for on-demand drug delivery |
| title_short | Electrically conductive “SMART” hydrogels for on-demand drug delivery |
| title_sort | electrically conductive smart hydrogels for on demand drug delivery |
| topic | Hydrogels Conductive polymers Electrically conductive hydrogels On-demand drug delivery |
| url | http://www.sciencedirect.com/science/article/pii/S1818087624001247 |
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