Health effects of occupational exposure to crystalline silica in the light of current research results

Crystalline silica is commonly found in the work environment. Possible health effects of occupational exposure continue to be the subject of extensive research. The aim of this paper was to analyze the recent findings concerning the health effects of exposure to crystalline silica, taking into accou...

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Main Author: Aleksandra Maciejewska
Format: Article
Language:English
Published: Nofer Institute of Occupational Medicine 2014-12-01
Series:Medycyna Pracy
Subjects:
Online Access:http://medpr.imp.lodz.pl/Zdrowotne-skutki-narazenia-zawodowego-na-krystaliczna-krzemionke-w-swietle-wynikow-aktualnych-badan,1956,0,1.html
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author Aleksandra Maciejewska
author_facet Aleksandra Maciejewska
author_sort Aleksandra Maciejewska
collection DOAJ
description Crystalline silica is commonly found in the work environment. Possible health effects of occupational exposure continue to be the subject of extensive research. The aim of this paper was to analyze the recent findings concerning the health effects of exposure to crystalline silica, taking into account different levels of exposure. This work is based on the relevant information from the papers retrieved from the following databases: EBSCO, Scopus, ScienceDirect, and Web of Science, using the following keywords: crystalline silica, quartz, health effects. The review of the results confirms the multi-faceted harmful effects of crystalline silica. Prolonged occupational exposure, apart from silicosis and non-cancer respiratory diseases, may also result in the development of lung cancer, and autoimmune and chronic kidney diseases, the pathogenesis, which has not been completely explained yet. The exposure to the crystalline silica at concentrations close to the current occupational exposure limit value does not exclude the risk of the following pathologies: silicosis, lung cancer, other lung diseases and renal diseases. It is not feasible to completely eliminate the crystalline silica dust from the work environment. The best way to reduce the health effects of the exposure is to minimize the concentrations of silica dust. Further progress in clarifying the true mechanisms of interaction between silica dust and lung cells, the determination of the importance of surface properties of the silica particles in the pathogenic processes and explaining the effects of co-morbid dust in the work environment may help to prevent the harmful effects of silica dust. Med Pr 2014;65(6):799–818
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spelling doaj.art-acf43b3cfa664abc8da032d5b114cb2f2022-12-22T03:56:45ZengNofer Institute of Occupational MedicineMedycyna Pracy0465-58932353-13392014-12-0165679981810.13075/mp.5893.00054Health effects of occupational exposure to crystalline silica in the light of current research resultsAleksandra MaciejewskaCrystalline silica is commonly found in the work environment. Possible health effects of occupational exposure continue to be the subject of extensive research. The aim of this paper was to analyze the recent findings concerning the health effects of exposure to crystalline silica, taking into account different levels of exposure. This work is based on the relevant information from the papers retrieved from the following databases: EBSCO, Scopus, ScienceDirect, and Web of Science, using the following keywords: crystalline silica, quartz, health effects. The review of the results confirms the multi-faceted harmful effects of crystalline silica. Prolonged occupational exposure, apart from silicosis and non-cancer respiratory diseases, may also result in the development of lung cancer, and autoimmune and chronic kidney diseases, the pathogenesis, which has not been completely explained yet. The exposure to the crystalline silica at concentrations close to the current occupational exposure limit value does not exclude the risk of the following pathologies: silicosis, lung cancer, other lung diseases and renal diseases. It is not feasible to completely eliminate the crystalline silica dust from the work environment. The best way to reduce the health effects of the exposure is to minimize the concentrations of silica dust. Further progress in clarifying the true mechanisms of interaction between silica dust and lung cells, the determination of the importance of surface properties of the silica particles in the pathogenic processes and explaining the effects of co-morbid dust in the work environment may help to prevent the harmful effects of silica dust. Med Pr 2014;65(6):799–818http://medpr.imp.lodz.pl/Zdrowotne-skutki-narazenia-zawodowego-na-krystaliczna-krzemionke-w-swietle-wynikow-aktualnych-badan,1956,0,1.htmlcrystalline silicaquartzsilicosishealth effectslung cancer
spellingShingle Aleksandra Maciejewska
Health effects of occupational exposure to crystalline silica in the light of current research results
Medycyna Pracy
crystalline silica
quartz
silicosis
health effects
lung cancer
title Health effects of occupational exposure to crystalline silica in the light of current research results
title_full Health effects of occupational exposure to crystalline silica in the light of current research results
title_fullStr Health effects of occupational exposure to crystalline silica in the light of current research results
title_full_unstemmed Health effects of occupational exposure to crystalline silica in the light of current research results
title_short Health effects of occupational exposure to crystalline silica in the light of current research results
title_sort health effects of occupational exposure to crystalline silica in the light of current research results
topic crystalline silica
quartz
silicosis
health effects
lung cancer
url http://medpr.imp.lodz.pl/Zdrowotne-skutki-narazenia-zawodowego-na-krystaliczna-krzemionke-w-swietle-wynikow-aktualnych-badan,1956,0,1.html
work_keys_str_mv AT aleksandramaciejewska healtheffectsofoccupationalexposuretocrystallinesilicainthelightofcurrentresearchresults