Biosynthetic tailoring of existing ascaroside pheromones alters their biological function in C. elegans

Biosynthetic tailoring of existing ascaroside pheromones alters their biological function in C. elegans

Caenorhabditis elegans produces ascaroside pheromones to control its development and behavior. Even minor structural differences in the ascarosides have dramatic consequences for their biological activities. Here, we identify a mechanism that enables C. elegans to dynamically tailor the fatty-acid s...

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Bibliographic Details
Main Authors: Yue Zhou, Yuting Wang, Xinxing Zhang, Subhradeep Bhar, Rachel A Jones Lipinski, Jungsoo Han, Likui Feng, Rebecca A Butcher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
ascarosides
dauer pheromone
beta-oxidation
acyl-CoA synthetase
acyl-CoA oxidase
peroxisome
Online Access:https://elifesciences.org/articles/33286

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