Brain Factor-7® Improves Cognitive Impairment Following Transient Ischemia and Reperfusion Injury in Gerbil Forebrain through Promoting Remyelination and Restoring Cholinergic and Glutamatergic Neurotransmission in the Hippocampus

Brain Factor-7® Improves Cognitive Impairment Following Transient Ischemia and Reperfusion Injury in Gerbil Forebrain through Promoting Remyelination and Restoring Cholinergic and Glutamatergic Neurotransmission in the Hippocampus

Background: Ischemia and reperfusion injury in the brain triggers cognitive impairment which are accompanied by neuronal death, loss of myelin sheath and decline in neurotransmission. In this study, we investigated whether therapeutic administration of Brain Factor-7® (BF-7®; a silk peptide) in isch...

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Bibliographic Details
Main Authors: Tae-Kyeong Lee, Sung-Su Kim, Ji-Won Lee, Dae Won Kim, Jae-Chul Lee, Jong-Dai Kim, Soo Young Choi, Seongkweon Hong, Moo-Ho Won, Yang Hee Kim
Format: Article
Language:English
Published: IMR Press 2022-12-01
Series:Frontiers in Bioscience-Landmark
Subjects:
cornu ammonis 1
memory function
neurotransmission
oligodendrocytes
pyramidal neuron
silk peptide
Online Access:https://www.imrpress.com/journal/FBL/27/12/10.31083/j.fbl2712337

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https://www.imrpress.com/journal/FBL/27/12/10.31083/j.fbl2712337

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