Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data

<p>Abstract</p> <p>Background</p> <p>The detection of genomic copy number alterations (CNA) in cancer based on SNP arrays requires methods that take into account tumour specific factors such as normal cell contamination and tumour heterogeneity. A number of tools have b...

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Bibliographic Details
Main Authors: Mosén-Ansorena David, Aransay Ana, Rodríguez-Ezpeleta Naiara
Format: Article
Language:English
Published: BMC 2012-08-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/192