Comparison of methods to detect copy number alterations in cancer using simulated and real genotyping data
<p>Abstract</p> <p>Background</p> <p>The detection of genomic copy number alterations (CNA) in cancer based on SNP arrays requires methods that take into account tumour specific factors such as normal cell contamination and tumour heterogeneity. A number of tools have b...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-08-01
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Series: | BMC Bioinformatics |
Online Access: | http://www.biomedcentral.com/1471-2105/13/192 |