From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits
Emotion influences various cognitive processes, including learning and memory. The amygdala is specialized for input and processing of emotion, while the hippocampus is essential for declarative or episodic memory. During emotional reactions, these two brain regions interact to translate the emotion...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2017-10-01
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| Series: | Frontiers in Neural Circuits |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fncir.2017.00086/full |
| _version_ | 1818982203021852672 |
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| author | Ying Yang Jian-Zhi Wang |
| author_facet | Ying Yang Jian-Zhi Wang |
| author_sort | Ying Yang |
| collection | DOAJ |
| description | Emotion influences various cognitive processes, including learning and memory. The amygdala is specialized for input and processing of emotion, while the hippocampus is essential for declarative or episodic memory. During emotional reactions, these two brain regions interact to translate the emotion into particular outcomes. Here, we briefly introduce the anatomy and functions of amygdala and hippocampus, and then present behavioral, electrophysiological, optogenetic and biochemical evidence from recent studies to illustrate how amygdala and hippocampus work synergistically to form long-term memory. With recent technological advances, the causal investigations of specific neural circuit between amygdala and hippocampus will help us understand the brain mechanisms of emotion-regulated memories and improve clinical treatment of emotion-associated memory disorders in patients. |
| first_indexed | 2024-12-20T17:43:29Z |
| format | Article |
| id | doaj.art-acfca084c3da4603aaf8ac8fd540a3f8 |
| institution | Directory Open Access Journal |
| issn | 1662-5110 |
| language | English |
| last_indexed | 2024-12-20T17:43:29Z |
| publishDate | 2017-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neural Circuits |
| spelling | doaj.art-acfca084c3da4603aaf8ac8fd540a3f82022-12-21T19:31:03ZengFrontiers Media S.A.Frontiers in Neural Circuits1662-51102017-10-011110.3389/fncir.2017.00086281732From Structure to Behavior in Basolateral Amygdala-Hippocampus CircuitsYing Yang0Jian-Zhi Wang1epartment of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Chinaepartment of Pathophysiology, School of Basic Medicine and the Collaborative Innovation Center for Brain Science, Key Laboratory of Ministry of Education of China for Neurological Disorders, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaEmotion influences various cognitive processes, including learning and memory. The amygdala is specialized for input and processing of emotion, while the hippocampus is essential for declarative or episodic memory. During emotional reactions, these two brain regions interact to translate the emotion into particular outcomes. Here, we briefly introduce the anatomy and functions of amygdala and hippocampus, and then present behavioral, electrophysiological, optogenetic and biochemical evidence from recent studies to illustrate how amygdala and hippocampus work synergistically to form long-term memory. With recent technological advances, the causal investigations of specific neural circuit between amygdala and hippocampus will help us understand the brain mechanisms of emotion-regulated memories and improve clinical treatment of emotion-associated memory disorders in patients.http://journal.frontiersin.org/article/10.3389/fncir.2017.00086/fullemotionmemoryamygdalahippocampusneural circuits |
| spellingShingle | Ying Yang Jian-Zhi Wang From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits Frontiers in Neural Circuits emotion memory amygdala hippocampus neural circuits |
| title | From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits |
| title_full | From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits |
| title_fullStr | From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits |
| title_full_unstemmed | From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits |
| title_short | From Structure to Behavior in Basolateral Amygdala-Hippocampus Circuits |
| title_sort | from structure to behavior in basolateral amygdala hippocampus circuits |
| topic | emotion memory amygdala hippocampus neural circuits |
| url | http://journal.frontiersin.org/article/10.3389/fncir.2017.00086/full |
| work_keys_str_mv | AT yingyang fromstructuretobehaviorinbasolateralamygdalahippocampuscircuits AT jianzhiwang fromstructuretobehaviorinbasolateralamygdalahippocampuscircuits |