Classification of cardiac excitation patterns during atrial fibrillation

The goal of this research was to classify cardiac excitation patterns during atrial fibrillation (AFib). For this purpose, virtual models of intracardiac mapping catheters were moved across in-silico cardiac tissue to extract local activation times (LATs) of each catheter electrode from simulated ca...

Full description

Bibliographic Details
Main Authors: Reich Christian, Oesterlein Tobias, Rottmann Markus, Seemann Gunnar, Dössel Olaf
Format: Article
Language:English
Published: De Gruyter 2016-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
Online Access:https://doi.org/10.1515/cdbme-2016-0037
_version_ 1819291542577217536
author Reich Christian
Oesterlein Tobias
Rottmann Markus
Seemann Gunnar
Dössel Olaf
author_facet Reich Christian
Oesterlein Tobias
Rottmann Markus
Seemann Gunnar
Dössel Olaf
author_sort Reich Christian
collection DOAJ
description The goal of this research was to classify cardiac excitation patterns during atrial fibrillation (AFib). For this purpose, virtual models of intracardiac mapping catheters were moved across in-silico cardiac tissue to extract local activation times (LATs) of each catheter electrode from simulated cardiac action potential (AP) signals. The resulting LAT patterns consisting of the LATs of all electrodes resemble patterns measured in clinical cases. The LATs represent the input information for features that were used to separate four different excitation patterns during AFib. Those four excitation patterns were plane wave, ectopic focus (spherical wave), rotor (spiral wave) and block. A feature selection algorithm was used to investigate the features concerning their power to classify the different simulated excitation patterns. The scores of the selected features were used to train and optimize a support vector machine (SVM). The optimized and cross-validated SVM was then used to classify the simulated cardiac excitation patterns. The achieved overall classification accuracy of this SVM model was 98.4 %.
first_indexed 2024-12-24T03:40:18Z
format Article
id doaj.art-ad007b399a304a3eb6ecb082dd2c8a48
institution Directory Open Access Journal
issn 2364-5504
language English
last_indexed 2024-12-24T03:40:18Z
publishDate 2016-09-01
publisher De Gruyter
record_format Article
series Current Directions in Biomedical Engineering
spelling doaj.art-ad007b399a304a3eb6ecb082dd2c8a482022-12-21T17:16:55ZengDe GruyterCurrent Directions in Biomedical Engineering2364-55042016-09-012116116610.1515/cdbme-2016-0037cdbme-2016-0037Classification of cardiac excitation patterns during atrial fibrillationReich Christian0Oesterlein Tobias1Rottmann Markus2Seemann Gunnar3Dössel Olaf4Karlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, GermanyKarlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, GermanyKarlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, GermanyKarlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, GermanyKarlsruhe Institute of Technology, Institute of Biomedical Engineering, Karlsruhe, GermanyThe goal of this research was to classify cardiac excitation patterns during atrial fibrillation (AFib). For this purpose, virtual models of intracardiac mapping catheters were moved across in-silico cardiac tissue to extract local activation times (LATs) of each catheter electrode from simulated cardiac action potential (AP) signals. The resulting LAT patterns consisting of the LATs of all electrodes resemble patterns measured in clinical cases. The LATs represent the input information for features that were used to separate four different excitation patterns during AFib. Those four excitation patterns were plane wave, ectopic focus (spherical wave), rotor (spiral wave) and block. A feature selection algorithm was used to investigate the features concerning their power to classify the different simulated excitation patterns. The scores of the selected features were used to train and optimize a support vector machine (SVM). The optimized and cross-validated SVM was then used to classify the simulated cardiac excitation patterns. The achieved overall classification accuracy of this SVM model was 98.4 %.https://doi.org/10.1515/cdbme-2016-0037atrial fibrillationclassificationexcitation patternlocal activation timesupport vector machine
spellingShingle Reich Christian
Oesterlein Tobias
Rottmann Markus
Seemann Gunnar
Dössel Olaf
Classification of cardiac excitation patterns during atrial fibrillation
Current Directions in Biomedical Engineering
atrial fibrillation
classification
excitation pattern
local activation time
support vector machine
title Classification of cardiac excitation patterns during atrial fibrillation
title_full Classification of cardiac excitation patterns during atrial fibrillation
title_fullStr Classification of cardiac excitation patterns during atrial fibrillation
title_full_unstemmed Classification of cardiac excitation patterns during atrial fibrillation
title_short Classification of cardiac excitation patterns during atrial fibrillation
title_sort classification of cardiac excitation patterns during atrial fibrillation
topic atrial fibrillation
classification
excitation pattern
local activation time
support vector machine
url https://doi.org/10.1515/cdbme-2016-0037
work_keys_str_mv AT reichchristian classificationofcardiacexcitationpatternsduringatrialfibrillation
AT oesterleintobias classificationofcardiacexcitationpatternsduringatrialfibrillation
AT rottmannmarkus classificationofcardiacexcitationpatternsduringatrialfibrillation
AT seemanngunnar classificationofcardiacexcitationpatternsduringatrialfibrillation
AT dosselolaf classificationofcardiacexcitationpatternsduringatrialfibrillation