Does Transcranial Direct Current Stimulation Combined with Peripheral Electrical Stimulation Have an Additive Effect in the Control of Hip Joint Osteonecrosis Pain Associated with Sickle Cell Disease? A Protocol for a One-Session Double Blind, Block-Randomized Clinical Trial

Does Transcranial Direct Current Stimulation Combined with Peripheral Electrical Stimulation Have an Additive Effect in the Control of Hip Joint Osteonecrosis Pain Associated with Sickle Cell Disease? A Protocol for a One-Session Double Blind, Block-Randomized Clinical Trial

Chronic pain in Sickle Cell Disease (SCD) is probably related to maladaptive plasticity of brain areas involved in nociceptive processing. Transcranial Direct Current Stimulation (tDCS) and Peripheral Electrical Stimulation (PES) can modulate cortical excitability and help to control chronic pain. S...

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Bibliographic Details
Main Authors: Tiago da Silva Lopes, Wellington dos Santos Silva, Sânzia B. Ribeiro, Camila A. Figueiredo, Fernanda Q. Campbell, Gildasio de Cerqueira Daltro, Antônio Valenzuela, Pedro Montoya, Rita de C. S. Lucena, Abrahão F. Baptista
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Human Neuroscience
Subjects:
neuromodulation
electroencephalography
sickle cell disease
BDNF
TNF
tDCS
Online Access:http://journal.frontiersin.org/article/10.3389/fnhum.2017.00633/full

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