Evaluation of the Anxiolytic and Anti-Epileptogenic Potential of <i>Lactuca Serriola</i> Seed Using Pentylenetetrazol-Induced Kindling in Mice and Metabolic Profiling of Its Bioactive Extract

Evaluation of the Anxiolytic and Anti-Epileptogenic Potential of <i>Lactuca Serriola</i> Seed Using Pentylenetetrazol-Induced Kindling in Mice and Metabolic Profiling of Its Bioactive Extract

This study aimed to assess the potential of <i>Lactuca serriola</i> (Asteraceae) seed <i>n</i>-hexane, chloroform, methanol, and aqueous extracts as anticonvulsant, sedative, anticonvulsant and antiepileptic agents in Swiss albino mice. Different doses of each extract were ev...

Full description

Bibliographic Details
Main Authors:	Muhammad Ihsan Ullah, Rukhsana Anwar, Shahzad Kamran, Bazgha Gul, Sameh S. Elhady, Fadia S. Youssef
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Antioxidants
Subjects:	<i>Lactuca serriola</i> anxiolytic anticonvulsant epilepsy Industrial development drug discovery
Online Access:	https://www.mdpi.com/2076-3921/11/11/2232

Similar Items

Germination and emergence of prickly lettuce (Lactuca serriola L.) and its susceptibility to selected herbicides
by: J. Mikulka, et al.
Published: (2003-02-01)

Neuropharmacological Effects of the Dichloromethane Extract from the Stems of <i>Argemone ochroleuca</i> Sweet (Papaveraceae) and Its Active Compound Dihydrosanguinarine
by: Eunice Yáñez-Barrientos, et al.
Published: (2023-08-01)

Neuropharmacological Activity of the Acetonic Extract of <i>Malpighia mexicana</i> A. Juss. and Its Phytochemical Profile
by: Dante Avilés-Montes, et al.
Published: (2023-10-01)

Leaf Blight Caused by Curvularia intermedia on the Invasive Weed Lactuca serriola in Korea
by: Jin A Lee, et al.
Published: (2023-09-01)

Eslicarbazepine, but Not Lamotrigine or Ranolazine, Shows Anticonvulsant Efficacy in Carbamazepine-Resistant Rats Developed by Window-Pentylenetetrazole Kindling
by: Cecilia Zavala-Tecuapetla, et al.
Published: (2022-05-01)

Effect of Acetaminophen (APAP) on Physiological Indicators in <i>Lactuca sativa</i>
by: Jiri Kudrna, et al.
Published: (2020-11-01)

LC/ESI/TOF-MS Characterization, Anxiolytic and Antidepressant-like Effects of <i>Mitragyna speciosa</i> Korth Extract in Diabetic Rats
by: Lin Chen, et al.
Published: (2022-03-01)

Risk Assessment of Psychotropic Drugs on Mitochondrial Function Using In Vitro Assays
by: Alicia Rosell-Hidalgo, et al.
Published: (2023-12-01)

Anxiolytic-<i>like</i> Effects by <i>trans</i>-Ferulic Acid Possibly Occur through GABAergic Interaction Pathways
by: Md. Shimul Bhuia, et al.
Published: (2023-09-01)

ANXIOLYTIC EFFECT OF HERBAL REMEDY «NOOPHYT»
by: Ya. G. Razuvaeva, et al.
Published: (2012-07-01)

<i>Ulva lactuca</i>, A Source of Troubles and Potential Riches
by: Herminia Dominguez, et al.
Published: (2019-06-01)

Chemical Composition of Essential Oil from Flower of ‘Shanzhizi’ (<i>Gardenia jasminoides</i> Ellis) and Involvement of Serotonergic System in Its Anxiolytic Effect
by: Nan Zhang, et al.
Published: (2020-10-01)

An Insight into the Anxiolytic and Antidepressant-Like Proprieties of <i>Carum carvi</i> L. and Their Association with Its Antioxidant Activity
by: Imane Es-safi, et al.
Published: (2021-03-01)

Preliminary Assessment of Four Wild Leafy Species to Be Used as Baby Salads
by: Ada Baldi, et al.
Published: (2023-06-01)

Chemical Composition of Lettuce (<i>Lactuca sativa</i> L.) Biofortified with Iodine by KIO<sub>3</sub>, 5-Iodo-, and 3.5-Diiodosalicylic Acid in a Hydroponic Cultivation
by: Olga Sularz, et al.
Published: (2020-07-01)

Evaluation of the neuropharmacologic potentials of methanol leaf extract of Cnidoscolus aconitifolius in mice
by: Wilson F. Iyare, et al.
Published: (2024-05-01)

Sedative Effects of Latexes Obtained from Some <i>Lactuca</i> L. Species Growing in Turkey
by: Selen Ilgün, et al.
Published: (2020-03-01)

Regulation of p53 Activity by (+)-Epiloliolide Isolated from <i>Ulva lactuca</i>
by: Yuheon Chung, et al.
Published: (2021-08-01)

Extraction of Bioactive Compounds from <i>Ulva lactuca</i>
by: Sofia Pappou, et al.
Published: (2022-02-01)

Essential Tea Tree Oil Activity against <i>Bremia lactucae</i> in Lettuce
by: Moshe Reuveni, et al.
Published: (2020-06-01)

Influence of Total Suspended Solids on the Growth of the Sea Lettuce <i>Ulva lactuca</i> Integrated with the Pacific White Shrimp <i>Litopenaeus vannamei</i> in a Biofloc System
by: Andrezza Carvalho, et al.
Published: (2023-03-01)

REGENERATION SYSTEM OF LETTUCE (<i>LACTUCA SATIVA</i> L.) THROUGH <i>IN VITRO</i> CULTURE
by: O. V. Romanova, et al.
Published: (2019-06-01)

Effect on Broiler Production Performance and Meat Quality of Feeding <i>Ulva lactuca</i> Supplemented with Carbohydrases
by: Mónica M. Costa, et al.
Published: (2022-07-01)

Nutritional Value and Biofunctionalities of Two Edible Green Seaweeds (<i>Ulva lactuca</i> and <i>Caulerpa racemosa</i>) from Indonesia by Subcritical Water Hydrolysis
by: Ratih Pangestuti, et al.
Published: (2021-10-01)

Evaluating the Endophytic Activities of <i>Beauveria bassiana</i> on the Physiology, Growth, and Antioxidant Activities of Extracts of Lettuce (<i>Lactuca sativa</i> L.)
by: Neo Macuphe, et al.
Published: (2021-06-01)

Antibacterial Activity and Anxiolytic Effect in Adult Zebrafish of Genus <i>Lippia</i> L. Species
by: Carla de Fatima Alves Nonato, et al.
Published: (2023-04-01)

Anti-Angiogenic/Anxiolytic Effect of Chlordiazepoxide: Evidence on Dual Activity for Cancer Patients
by: Reza Yarani, et al.
Published: (2011-09-01)

Effects of Fertilization Mode on the Growth of <i>Lactuca sativa</i> L. and Soil Nutrients in Facilitated Cultivation
by: Wei Li, et al.
Published: (2023-08-01)

A Molecular Docking Study on Natural Compounds as Anxiolytics and Antidepressants
by: Maria Mernea, et al.
Published: (2022-11-01)

Protective Effects of <i>Ulva lactuca</i> Polysaccharide Extract on Oxidative Stress and Kidney Injury Induced by D-Galactose in Mice
by: Qian Yang, et al.
Published: (2021-09-01)

Use of <i>Chlorella vulgaris</i> and <i>Ulva lactuca</i> as Biostimulant on Lettuce
by: Chiara Ammaturo, et al.
Published: (2023-08-01)

Anxiolytic, Antidepressant-Like Proprieties and Impact on the Memory of the Hydro-Ethanolic Extract of <i>Origanum majorana</i> L. on Mice
by: Amal Amaghnouje, et al.
Published: (2020-11-01)

Acute and Chronic Effects of N-acetylcysteine on Pentylenetetrazole-induced Seizure and Neuromuscular Coordination in Mice
by: Sasan Zaeri, et al.
Published: (2015-03-01)

Extracts of <i>Ulva lactuca</i> Induce Responses against <i>Penicillium digitatum</i> on Oranges
by: Douaa Salim, et al.
Published: (2023-03-01)

Plasma Metabolites and Liver Composition of Broilers in Response to Dietary <i>Ulva lactuca</i> with Ulvan Lyase or a Commercial Enzyme Mixture
by: Cristina M. Alfaia, et al.
Published: (2022-11-01)

Factors Affecting Efficiency of Biosorption of Fe (III) and Zn (II) by <i>Ulva lactuca</i> and <i>Corallina officinalis</i> and Their Activated Carbons
by: Mahy M. Ameen, et al.
Published: (2021-12-01)

Prospective Antiviral Effect of <i>Ulva lactuca</i> Aqueous Extract against COVID-19 Infection
by: Reem Binsuwaidan, et al.
Published: (2023-12-01)

Regulation of Carotenoid Biosynthesis and Degradation in Lettuce (<i>Lactuca sativa</i> L.) from Seedlings to Harvest
by: Galina Brychkova, et al.
Published: (2023-06-01)

Possibilities of Anxiolytic Therapy in the Elimination of Stress Skin Manifestations: A Case Report
by: Nataliia Sydorova, et al.
Published: (2023-05-01)

Use of anxiolytics and hypnotic drugs during COVID-19 pandemic: The literature review
by: Trajkovski Tea, et al.
Published: (2022-01-01)