Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report
<p>Abstract</p> <p>Background</p> <p>Dome-type carcinoma (DC) is a distinct variant of colorectal adenocarcinoma and less than 10 cases have been described in the literature. Most of the previously reported cases were early lesions and no endoscopic observations have be...
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| Format: | Article |
| Language: | English |
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BMC
2012-03-01
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| Series: | BMC Gastroenterology |
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| Online Access: | http://www.biomedcentral.com/1471-230X/12/21 |
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| author | Yamada Masayoshi Sekine Shigeki Matsuda Takahisa Yoshida Masayuki Taniguchi Hirokazu Kushima Ryoji Sakamoto Taku Nakajima Takeshi Saito Yutaka Akasu Takayuki |
| author_facet | Yamada Masayoshi Sekine Shigeki Matsuda Takahisa Yoshida Masayuki Taniguchi Hirokazu Kushima Ryoji Sakamoto Taku Nakajima Takeshi Saito Yutaka Akasu Takayuki |
| author_sort | Yamada Masayoshi |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Dome-type carcinoma (DC) is a distinct variant of colorectal adenocarcinoma and less than 10 cases have been described in the literature. Most of the previously reported cases were early lesions and no endoscopic observations have been described so far. We herein report a case of a DC invading the subserosal layer, including endoscopic findings.</p> <p>Case presentation</p> <p>A highly elevated lesion in the transverse colon was diagnosed by colonoscopy in a 77-year-old man. The tumor appeared to be similar to a submucosal tumor (SMT), however, a demarcated area of reddish and irregular mucosa was observed at the top of the tumor. There were no erosions or ulcers. Laparoscopic-assisted right hemicolectomy was performed and pathological examination revealed a well-circumscribed tumor invading the subserosal layer. The tumor was a well-differentiated adenocarcinoma associated with a dense lymphocytic infiltration and showed expansive growth. The overlying mucosal layer showed high-grade dysplasia.</p> <p>Conclusion</p> <p>The present lesion was diagnosed as a DC of the colon invading the subserosal layer. Because the association of mucosal dysplasia is common in DCs, the detection of dysplastic epithelium would be important to discriminate DCs from SMTs.</p> |
| first_indexed | 2024-12-22T22:24:09Z |
| format | Article |
| id | doaj.art-ad03621fcd5d4d36b0a5e1c557d8fd16 |
| institution | Directory Open Access Journal |
| issn | 1471-230X |
| language | English |
| last_indexed | 2024-12-22T22:24:09Z |
| publishDate | 2012-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Gastroenterology |
| spelling | doaj.art-ad03621fcd5d4d36b0a5e1c557d8fd162022-12-21T18:10:35ZengBMCBMC Gastroenterology1471-230X2012-03-011212110.1186/1471-230X-12-21Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case reportYamada MasayoshiSekine ShigekiMatsuda TakahisaYoshida MasayukiTaniguchi HirokazuKushima RyojiSakamoto TakuNakajima TakeshiSaito YutakaAkasu Takayuki<p>Abstract</p> <p>Background</p> <p>Dome-type carcinoma (DC) is a distinct variant of colorectal adenocarcinoma and less than 10 cases have been described in the literature. Most of the previously reported cases were early lesions and no endoscopic observations have been described so far. We herein report a case of a DC invading the subserosal layer, including endoscopic findings.</p> <p>Case presentation</p> <p>A highly elevated lesion in the transverse colon was diagnosed by colonoscopy in a 77-year-old man. The tumor appeared to be similar to a submucosal tumor (SMT), however, a demarcated area of reddish and irregular mucosa was observed at the top of the tumor. There were no erosions or ulcers. Laparoscopic-assisted right hemicolectomy was performed and pathological examination revealed a well-circumscribed tumor invading the subserosal layer. The tumor was a well-differentiated adenocarcinoma associated with a dense lymphocytic infiltration and showed expansive growth. The overlying mucosal layer showed high-grade dysplasia.</p> <p>Conclusion</p> <p>The present lesion was diagnosed as a DC of the colon invading the subserosal layer. Because the association of mucosal dysplasia is common in DCs, the detection of dysplastic epithelium would be important to discriminate DCs from SMTs.</p>http://www.biomedcentral.com/1471-230X/12/21Colorectal carcinomaGut-associated lymphoid tissueDome-type carcinoma |
| spellingShingle | Yamada Masayoshi Sekine Shigeki Matsuda Takahisa Yoshida Masayuki Taniguchi Hirokazu Kushima Ryoji Sakamoto Taku Nakajima Takeshi Saito Yutaka Akasu Takayuki Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report BMC Gastroenterology Colorectal carcinoma Gut-associated lymphoid tissue Dome-type carcinoma |
| title | Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report |
| title_full | Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report |
| title_fullStr | Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report |
| title_full_unstemmed | Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report |
| title_short | Dome-type carcinoma of the colon; a rare variant of adenocarcinoma resembling a submucosal tumor: a case report |
| title_sort | dome type carcinoma of the colon a rare variant of adenocarcinoma resembling a submucosal tumor a case report |
| topic | Colorectal carcinoma Gut-associated lymphoid tissue Dome-type carcinoma |
| url | http://www.biomedcentral.com/1471-230X/12/21 |
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