Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study
Purpose To assess the feasibility, efficacy, and safety of ultrasound (US)-guided microwave ablation (MWA) for the treatment of papillary thyroid cancer (PTC) located in the thyroid isthmus. Materials and methods Thirty-four patients (mean age, 43 ± 11 years; 26 women) with isthmic PTC treated with...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-01-01
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| Series: | International Journal of Hyperthermia |
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| Online Access: | http://dx.doi.org/10.1080/02656736.2021.1880028 |
| _version_ | 1818967602782797824 |
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| author | Xiao-Jing Cao Zhen-Long Zhao Ying Wei Li-Li Peng Yan Li Jie Wu Ming-An Yu |
| author_facet | Xiao-Jing Cao Zhen-Long Zhao Ying Wei Li-Li Peng Yan Li Jie Wu Ming-An Yu |
| author_sort | Xiao-Jing Cao |
| collection | DOAJ |
| description | Purpose To assess the feasibility, efficacy, and safety of ultrasound (US)-guided microwave ablation (MWA) for the treatment of papillary thyroid cancer (PTC) located in the thyroid isthmus. Materials and methods Thirty-four patients (mean age, 43 ± 11 years; 26 women) with isthmic PTC treated with MWA between June 2014 and September 2020 were included in this retrospective study. The follow-up time after MWA was 17 ± 9 months (range, 8–50 months). Changes in thyroid function, parathyroid function, and tumor size were evaluated, along with the rates of tumor disappearance and complications. Results The treatment was technically feasible and successfully completed in all 34 patients (100%). Measures of thyroid function (i.e. serum triiodothyronine, free thyroxine, and thyrotropin) and parathyroid function (i.e. serum calcium and intact parathyroid hormone) showed no changes from pretreatment levels at 1, 3, and 6 months after MWA (p > 0.05 for all). Tumor size was found to be increased at 1 and 3 months after MWA compared with before MWA (p < 0.05). However, the tumor sizes measured at 6, 9, 12, and 18 months after MWA were smaller than the pretreatment sizes (p < 0.05 for all). In 24 cases (70.6%), the tumors completely disappeared on US examination. Five cases (2.9%) experienced side effects from MWA treatment, but no major or minor complications were recorded. Conclusion The results of this study demonstrate that US-guided MWA is a feasible, effective, and safe treatment option for selected patients with PTC located in the thyroid isthmus. |
| first_indexed | 2024-12-20T13:51:25Z |
| format | Article |
| id | doaj.art-ad065caf6a9d43bd9387189ceff06b36 |
| institution | Directory Open Access Journal |
| issn | 0265-6736 1464-5157 |
| language | English |
| last_indexed | 2024-12-20T13:51:25Z |
| publishDate | 2021-01-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | International Journal of Hyperthermia |
| spelling | doaj.art-ad065caf6a9d43bd9387189ceff06b362022-12-21T19:38:31ZengTaylor & Francis GroupInternational Journal of Hyperthermia0265-67361464-51572021-01-0138111411910.1080/02656736.2021.18800281880028Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary studyXiao-Jing Cao0Zhen-Long Zhao1Ying Wei2Li-Li Peng3Yan Li4Jie Wu5Ming-An Yu6Department of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalDepartment of Interventional Medicine, China-Japan Friendship HospitalPurpose To assess the feasibility, efficacy, and safety of ultrasound (US)-guided microwave ablation (MWA) for the treatment of papillary thyroid cancer (PTC) located in the thyroid isthmus. Materials and methods Thirty-four patients (mean age, 43 ± 11 years; 26 women) with isthmic PTC treated with MWA between June 2014 and September 2020 were included in this retrospective study. The follow-up time after MWA was 17 ± 9 months (range, 8–50 months). Changes in thyroid function, parathyroid function, and tumor size were evaluated, along with the rates of tumor disappearance and complications. Results The treatment was technically feasible and successfully completed in all 34 patients (100%). Measures of thyroid function (i.e. serum triiodothyronine, free thyroxine, and thyrotropin) and parathyroid function (i.e. serum calcium and intact parathyroid hormone) showed no changes from pretreatment levels at 1, 3, and 6 months after MWA (p > 0.05 for all). Tumor size was found to be increased at 1 and 3 months after MWA compared with before MWA (p < 0.05). However, the tumor sizes measured at 6, 9, 12, and 18 months after MWA were smaller than the pretreatment sizes (p < 0.05 for all). In 24 cases (70.6%), the tumors completely disappeared on US examination. Five cases (2.9%) experienced side effects from MWA treatment, but no major or minor complications were recorded. Conclusion The results of this study demonstrate that US-guided MWA is a feasible, effective, and safe treatment option for selected patients with PTC located in the thyroid isthmus.http://dx.doi.org/10.1080/02656736.2021.1880028papillarythyroidcanceristhmusmicrowave ablation |
| spellingShingle | Xiao-Jing Cao Zhen-Long Zhao Ying Wei Li-Li Peng Yan Li Jie Wu Ming-An Yu Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study International Journal of Hyperthermia papillary thyroid cancer isthmus microwave ablation |
| title | Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study |
| title_full | Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study |
| title_fullStr | Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study |
| title_full_unstemmed | Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study |
| title_short | Microwave ablation for papillary thyroid cancer located in the thyroid isthmus: a preliminary study |
| title_sort | microwave ablation for papillary thyroid cancer located in the thyroid isthmus a preliminary study |
| topic | papillary thyroid cancer isthmus microwave ablation |
| url | http://dx.doi.org/10.1080/02656736.2021.1880028 |
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