Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020
Background and purpose: Coronavirus Disease-2019) COVID-19) is a respiratory infection which was recognized as a pandemic by the world health organization on march 11, 2020. This study aimed to evaluate new treatment modalities therapy in management of COVID-19. Materials and methods: A descriptive-...
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| Format: | Article |
| Language: | English |
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Mazandaran University of Medical Sciences
2021-05-01
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| Series: | Journal of Mazandaran University of Medical Sciences |
| Subjects: | |
| Online Access: | http://jmums.mazums.ac.ir/article-1-16156-en.html |
| _version_ | 1797944021289533440 |
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| author | Ahmad Alikhani Masoud Maboudi Mohammad Khademloo Azadeh Khalatbari |
| author_facet | Ahmad Alikhani Masoud Maboudi Mohammad Khademloo Azadeh Khalatbari |
| author_sort | Ahmad Alikhani |
| collection | DOAJ |
| description | Background and purpose: Coronavirus Disease-2019) COVID-19) is a respiratory infection which was recognized as a pandemic by the world health organization on march 11, 2020. This study aimed to evaluate new treatment modalities therapy in management of COVID-19.
Materials and methods: A descriptive-analytical, retrospective study was performed in patients over 17 years of age with suspected COVID-19 admitted to Qaemshahar Razi Hospital in March and April 2020. The case group included patients treated with methylprednisolone, intravenous immunoglobulin (IVIg), Beta Interferon, Ribavirin, Arbidol, Remdesivir, Favipiravir and Hydroxychloroquine and lopinavir/ritonavir. The control group was selected from hospitalized cases who were treated only with lopinavir/ritonavir and Hydroxychloroquine. This study evaluated the efficacy of these drugs. Data was analyzed in SPSS V18.
Results: The mean ages of case group (n=217) and control group were 54.23±16.64 (17-88) years and 53.8±16.23 (19-80) years, respectively. The need for ICU admission and mechanical ventilation were significantly different between the two groups (P<0.05) but no significant difference was seen on mortality rate (P>0.05).
Conclusion: Using anti-inflammatory and anti-viral drugs in hospitalized patients seems reasonable until widespread vaccination and development of effective drug. |
| first_indexed | 2024-04-10T20:33:10Z |
| format | Article |
| id | doaj.art-ad0cecc2054d43c4bddf1913c24e8fd1 |
| institution | Directory Open Access Journal |
| issn | 1735-9260 1735-9279 |
| language | English |
| last_indexed | 2024-04-10T20:33:10Z |
| publishDate | 2021-05-01 |
| publisher | Mazandaran University of Medical Sciences |
| record_format | Article |
| series | Journal of Mazandaran University of Medical Sciences |
| spelling | doaj.art-ad0cecc2054d43c4bddf1913c24e8fd12023-01-25T05:13:23ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792021-05-01311964451Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020Ahmad Alikhani0Masoud Maboudi1Mohammad Khademloo2Azadeh Khalatbari3 Associate Professor, Department of Infectious Diseases, Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran 3 Resident in Infectious Diseases, Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran Associate Professor, Department of Community Medicine, Mazandaran University of Medical Sciences, Sari, Iran General Practitioner, Antimicrobial Resistance Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, IranFaculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran Background and purpose: Coronavirus Disease-2019) COVID-19) is a respiratory infection which was recognized as a pandemic by the world health organization on march 11, 2020. This study aimed to evaluate new treatment modalities therapy in management of COVID-19. Materials and methods: A descriptive-analytical, retrospective study was performed in patients over 17 years of age with suspected COVID-19 admitted to Qaemshahar Razi Hospital in March and April 2020. The case group included patients treated with methylprednisolone, intravenous immunoglobulin (IVIg), Beta Interferon, Ribavirin, Arbidol, Remdesivir, Favipiravir and Hydroxychloroquine and lopinavir/ritonavir. The control group was selected from hospitalized cases who were treated only with lopinavir/ritonavir and Hydroxychloroquine. This study evaluated the efficacy of these drugs. Data was analyzed in SPSS V18. Results: The mean ages of case group (n=217) and control group were 54.23±16.64 (17-88) years and 53.8±16.23 (19-80) years, respectively. The need for ICU admission and mechanical ventilation were significantly different between the two groups (P<0.05) but no significant difference was seen on mortality rate (P>0.05). Conclusion: Using anti-inflammatory and anti-viral drugs in hospitalized patients seems reasonable until widespread vaccination and development of effective drug.http://jmums.mazums.ac.ir/article-1-16156-en.htmlcoronavirus disease-2019covid-19 drug treatmentcovid-19 immunoglobulin therapy |
| spellingShingle | Ahmad Alikhani Masoud Maboudi Mohammad Khademloo Azadeh Khalatbari Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 Journal of Mazandaran University of Medical Sciences coronavirus disease-2019 covid-19 drug treatment covid-19 immunoglobulin therapy |
| title | Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 |
| title_full | Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 |
| title_fullStr | Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 |
| title_full_unstemmed | Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 |
| title_short | Efficacy of New Treatment Modalities in Patients with COVID-19, Qaemshahar Razi Hospital 2020 |
| title_sort | efficacy of new treatment modalities in patients with covid 19 qaemshahar razi hospital 2020 |
| topic | coronavirus disease-2019 covid-19 drug treatment covid-19 immunoglobulin therapy |
| url | http://jmums.mazums.ac.ir/article-1-16156-en.html |
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