A standardized methodical approach to characterize the influence of key parameters on the in vitro efficacy of extracorporeal photopheresis.

A standardized methodical approach to characterize the influence of key parameters on the in vitro efficacy of extracorporeal photopheresis.

Extracorporeal photopheresis (ECP) is an autologous immunomodulatory cell therapy that consists of the ex vivo collection of mononuclear cells (MNCs), which are irradiated with UVA in the presence of the photosensitizing agent 8-methoxypsoralen (8-MOP) to induce cell apoptosis. This photoactivated c...

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Bibliographic Details
Main Authors: Marie Laulhé, Sylvie Lefebvre, Delphine Le Broc-Ryckewaert, Maxime Pierre, Aurélie Ferry, Bruno Delorme
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212835

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