Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients

Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients

Alzheimer’s disease (AD) is an incurable neurodegenerative disorder with a few early detection strategies. We previously proposed the amyloid precursor protein (APP) tyrosine 682 (Tyr682) residue as a valuable target for the development of new innovative pharmacologic or diagnostic interventions in...

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Bibliographic Details
Main Authors: Filomena Iannuzzi, Rossana Sirabella, Nadia Canu, Thorsten J. Maier, Lucio Annunziato, Carmela Matrone
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cells
Subjects:
amyloid precursor protein
amyloid beta
Fyn tyrosine kinase
Tyr682 residue
YENPTY domain
Online Access:https://www.mdpi.com/2073-4409/9/8/1807

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