Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images

Modeling, validation and verification of three-dimensional cell-scaffold contacts from terabyte-sized images

Abstract Background Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and three types of scaffolds (i.e., spun coat, large microfiber, and medium microfiber). Our analysis of...

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Bibliographic Details
Main Authors: Peter Bajcsy, Soweon Yoon, Stephen J. Florczyk, Nathan A. Hotaling, Mylene Simon, Piotr M. Szczypinski, Nicholas J. Schaub, Carl G. Simon, Mary Brady, Ram D. Sriram
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Bioinformatics
Subjects:
Co-localization
Cellular measurements
Cell-scaffold contact
Segmentation models
Contact evaluation
Web-based verification
Online Access:http://link.springer.com/article/10.1186/s12859-017-1928-x

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