Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using...

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Main Authors: Falah Saleh Mohammed, Mustafa Pehlivan, Mustafa Sevindik
Format: Article
Language:English
Published: International Journal of Secondary Metabolite 2020-01-01
Series:International Journal of Secondary Metabolite
Subjects:
Online Access:https://dergipark.org.tr/tr/pub/ijsm/issue/50293/581500?publisher=ijate
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author Falah Saleh Mohammed
Mustafa Pehlivan
Mustafa Sevindik
author_facet Falah Saleh Mohammed
Mustafa Pehlivan
Mustafa Sevindik
author_sort Falah Saleh Mohammed
collection DOAJ
description In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations.  Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.
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spelling doaj.art-ad1925ed0b12422ca0c92328c813e1832023-02-15T16:11:29ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052020-01-016431732210.21448/ijsm.581500618Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)Falah Saleh MohammedMustafa Pehlivan0Mustafa Sevindik1Gaziantep UniversityAKDENIZ UNIVERSITYIn this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations.  Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.https://dergipark.org.tr/tr/pub/ijsm/issue/50293/581500?publisher=ijateantioxidantantibacterialantifungalmedicinal plantssilybum marianum
spellingShingle Falah Saleh Mohammed
Mustafa Pehlivan
Mustafa Sevindik
Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
International Journal of Secondary Metabolite
antioxidant
antibacterial
antifungal
medicinal plants
silybum marianum
title Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
title_full Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
title_fullStr Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
title_full_unstemmed Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
title_short Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)
title_sort antioxidant antibacterial and antifungal activities of different extracts of silybum marianum collected from duhok iraq
topic antioxidant
antibacterial
antifungal
medicinal plants
silybum marianum
url https://dergipark.org.tr/tr/pub/ijsm/issue/50293/581500?publisher=ijate
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AT mustafapehlivan antioxidantantibacterialandantifungalactivitiesofdifferentextractsofsilybummarianumcollectedfromduhokiraq
AT mustafasevindik antioxidantantibacterialandantifungalactivitiesofdifferentextractsofsilybummarianumcollectedfromduhokiraq