Alpha-Gal on the Protein Surface Hampers Transcytosis through the Caco-2 Monolayer

Alpha-Gal on the Protein Surface Hampers Transcytosis through the Caco-2 Monolayer

Transepithelial transport of proteins is an important step in the immune response to food allergens. Mammalian meat allergy is characterized by an IgE response against the carbohydrate moiety galactosyl-α-1,3-galactose (α-Gal) present on mammalian glycoproteins and glycolipids, which causes severe a...

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Bibliographic Details
Main Authors: Maja Krstić Ristivojević, Jeanette Grundström, Danijela Apostolović, Mirjana Radomirović, Vesna Jovanović, Vlad Radoi, M. B. Gea Kiewiet, Vladana Vukojević, Tanja Ćirković Veličković, Marianne van Hage
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
α-Gal
transcytosis
glycoprotein
glycans
Caco-2 cells
mammalian meat allergy
Online Access:https://www.mdpi.com/1422-0067/21/16/5742

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