Preliminary analysis of immune-related markers in thymic carcinoid
Abstract The immune-related microenvironment of thymic carcinoid has rarely been reported. We analyzed the expression of PD-L1 and VISTA, and the distribution of CD4+ T cells, CD8+ T cells and CD68+ macrophages in the thymic carcinoid by immunohistochemical staining, and showed the correlation betwe...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-12-01
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| Series: | Journal of Translational Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12967-023-04751-x |
| _version_ | 1797397829966102528 |
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| author | Jiaqi Zhang Chao Guo Lei Liu Ke Zhao Mengxin Zhou Yeye Chen Shanqing Li |
| author_facet | Jiaqi Zhang Chao Guo Lei Liu Ke Zhao Mengxin Zhou Yeye Chen Shanqing Li |
| author_sort | Jiaqi Zhang |
| collection | DOAJ |
| description | Abstract The immune-related microenvironment of thymic carcinoid has rarely been reported. We analyzed the expression of PD-L1 and VISTA, and the distribution of CD4+ T cells, CD8+ T cells and CD68+ macrophages in the thymic carcinoid by immunohistochemical staining, and showed the correlation between these markers and clinical survival, indicating the potential therapeutic prospects. |
| first_indexed | 2024-03-09T01:15:52Z |
| format | Article |
| id | doaj.art-ad298170d9d9468699a0e6071e29efb9 |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-03-09T01:15:52Z |
| publishDate | 2023-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-ad298170d9d9468699a0e6071e29efb92023-12-10T12:29:49ZengBMCJournal of Translational Medicine1479-58762023-12-012111310.1186/s12967-023-04751-xPreliminary analysis of immune-related markers in thymic carcinoidJiaqi Zhang0Chao Guo1Lei Liu2Ke Zhao3Mengxin Zhou4Yeye Chen5Shanqing Li6Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeDepartment of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeAbstract The immune-related microenvironment of thymic carcinoid has rarely been reported. We analyzed the expression of PD-L1 and VISTA, and the distribution of CD4+ T cells, CD8+ T cells and CD68+ macrophages in the thymic carcinoid by immunohistochemical staining, and showed the correlation between these markers and clinical survival, indicating the potential therapeutic prospects.https://doi.org/10.1186/s12967-023-04751-xThymic carcinoidImmune-related microenvironmentPD-L1VISTA |
| spellingShingle | Jiaqi Zhang Chao Guo Lei Liu Ke Zhao Mengxin Zhou Yeye Chen Shanqing Li Preliminary analysis of immune-related markers in thymic carcinoid Journal of Translational Medicine Thymic carcinoid Immune-related microenvironment PD-L1 VISTA |
| title | Preliminary analysis of immune-related markers in thymic carcinoid |
| title_full | Preliminary analysis of immune-related markers in thymic carcinoid |
| title_fullStr | Preliminary analysis of immune-related markers in thymic carcinoid |
| title_full_unstemmed | Preliminary analysis of immune-related markers in thymic carcinoid |
| title_short | Preliminary analysis of immune-related markers in thymic carcinoid |
| title_sort | preliminary analysis of immune related markers in thymic carcinoid |
| topic | Thymic carcinoid Immune-related microenvironment PD-L1 VISTA |
| url | https://doi.org/10.1186/s12967-023-04751-x |
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