Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells

Endothelin Receptor Down-Regulation Mediated Ligand Regulation Mechanisms Protect Against Cellular Hypoxia Injury in Rat Vascular Endothelial Cells

Objective: Investigation of the effect of endothelin receptor A (ETaR)-targeting small interfering RNA (siRNA) on rat vascular endothelial cellular hypoxia injury, as well as its underlying mechanism. Methods: An in vitro rat vascular smooth muscle cells - endothelial cells co-culture model was esta...

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Bibliographic Details
Main Authors: Long Li, Mushuang Hu, Long Zheng, Chao Zhang, Jiawei Li, Ruiming Rong, Tongyu Zhu, Yichen Jia
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Endothelin receptor
Small interfering RNA
Endothelial cells
Co-culture
Online Access:http://www.karger.com/Article/FullText/453196

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