Circadian rhythm and heart disease - what is the link? A review

Introduction and purpose: Cardiovascular disease (CVD) is still the leading cause of death worldwide and causes 49% of mortality in Europe. This makes CVD is the most important reason for premature mortality and Disability Adjusted Life Years (“DALYS”) in that continent. It is associated with varia...

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Main Authors: Agnieszka Brzezińska, Aleksandra Skorupa, Aleksandra Nowińska, Justyna Nowaczek
Format: Article
Language:English
Published: Kazimierz Wielki University 2022-11-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:https://apcz.umk.pl/JEHS/article/view/40175
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author Agnieszka Brzezińska
Aleksandra Skorupa
Aleksandra Nowińska
Justyna Nowaczek
author_facet Agnieszka Brzezińska
Aleksandra Skorupa
Aleksandra Nowińska
Justyna Nowaczek
author_sort Agnieszka Brzezińska
collection DOAJ
description Introduction and purpose: Cardiovascular disease (CVD) is still the leading cause of death worldwide and causes 49% of mortality in Europe. This makes CVD is the most important reason for premature mortality and Disability Adjusted Life Years (“DALYS”) in that continent. It is associated with variables such as blood pressure, heart rate, circulating catecholamines, markers of blood coagulation and vascular endothelial function which are dependent on different times of the day. The epidemiological data indicate that the biggest number of CVD incidents occur during the early morning hours. In this work we try to discuss the circadian rhythm and its impact on variables which, according to data, are most crucial on CV incident rate. Brief description of the state of knowledge: The cardiovascular disease and mortality risk is associated with variables such as morning blood pressure, fluctuations in metabolism rate or even in immunological response. These variables are dependent on the circadian rhythm. This article covers the most crucial components affected by the daily fluctuations considering the heart according to the literature from the last five years.  Conclusions: This review highlighted the link between circadian rhythm and cardiovascular disease with the purpose of focusing on the most important clinically aspects of that machinery from blood pressure to inflammation. Despite all of these exciting findings which could possibly have future implications in the field of cardiology, there is still a significant need to explore this complicated relationship between the biological clock and the heart. 
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spelling doaj.art-ad3bc24946af4074af30b7d91419c6b12022-12-22T04:14:45ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062022-11-01121210.12775/JEHS.2022.12.12.007Circadian rhythm and heart disease - what is the link? A reviewAgnieszka Brzezińska0Aleksandra Skorupa1Aleksandra Nowińska2Justyna Nowaczek3Uniwersytet Medyczny w LublinieUniwersytet Medyczny w Lublinie, Aleje Racławickie 1, 20-089 LublinUniwersytet Medyczny w Lublinie, Aleje Racławickie 1, 20-089 LublinUniwersytet Medyczny w Lublinie, Aleje Racławickie 1, 20-89 Lublin Introduction and purpose: Cardiovascular disease (CVD) is still the leading cause of death worldwide and causes 49% of mortality in Europe. This makes CVD is the most important reason for premature mortality and Disability Adjusted Life Years (“DALYS”) in that continent. It is associated with variables such as blood pressure, heart rate, circulating catecholamines, markers of blood coagulation and vascular endothelial function which are dependent on different times of the day. The epidemiological data indicate that the biggest number of CVD incidents occur during the early morning hours. In this work we try to discuss the circadian rhythm and its impact on variables which, according to data, are most crucial on CV incident rate. Brief description of the state of knowledge: The cardiovascular disease and mortality risk is associated with variables such as morning blood pressure, fluctuations in metabolism rate or even in immunological response. These variables are dependent on the circadian rhythm. This article covers the most crucial components affected by the daily fluctuations considering the heart according to the literature from the last five years.  Conclusions: This review highlighted the link between circadian rhythm and cardiovascular disease with the purpose of focusing on the most important clinically aspects of that machinery from blood pressure to inflammation. Despite all of these exciting findings which could possibly have future implications in the field of cardiology, there is still a significant need to explore this complicated relationship between the biological clock and the heart.  https://apcz.umk.pl/JEHS/article/view/40175Circadian rhythmBlood pressureChronotherapyCardiovascular disease
spellingShingle Agnieszka Brzezińska
Aleksandra Skorupa
Aleksandra Nowińska
Justyna Nowaczek
Circadian rhythm and heart disease - what is the link? A review
Journal of Education, Health and Sport
Circadian rhythm
Blood pressure
Chronotherapy
Cardiovascular disease
title Circadian rhythm and heart disease - what is the link? A review
title_full Circadian rhythm and heart disease - what is the link? A review
title_fullStr Circadian rhythm and heart disease - what is the link? A review
title_full_unstemmed Circadian rhythm and heart disease - what is the link? A review
title_short Circadian rhythm and heart disease - what is the link? A review
title_sort circadian rhythm and heart disease what is the link a review
topic Circadian rhythm
Blood pressure
Chronotherapy
Cardiovascular disease
url https://apcz.umk.pl/JEHS/article/view/40175
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