The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study
<h4>Background</h4> The diagnosis of acute mountain sickness, which lacks a reliable and objective diagnostic tool, still depends on the clinical symptoms and signs and remains a major threat and unpredictable disease affecting millions of mountaineers. <h4>Objectives</h4> To...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683632/?tool=EBI |
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| author | Kuo-Song Chang Yu-Hui Chiu Wei-Fong Kao Cheryl C. H. Yang Chorng-Kuang How Yen-Kuang Lin Yuh-Shyan Hwang Ding-Kuo Chien Ming-Kun Huang Terry B. J. Kuo |
| author_facet | Kuo-Song Chang Yu-Hui Chiu Wei-Fong Kao Cheryl C. H. Yang Chorng-Kuang How Yen-Kuang Lin Yuh-Shyan Hwang Ding-Kuo Chien Ming-Kun Huang Terry B. J. Kuo |
| author_sort | Kuo-Song Chang |
| collection | DOAJ |
| description | <h4>Background</h4> The diagnosis of acute mountain sickness, which lacks a reliable and objective diagnostic tool, still depends on the clinical symptoms and signs and remains a major threat and unpredictable disease affecting millions of mountaineers. <h4>Objectives</h4> To record electroencephalography signals with small, convenient, wireless equipment and to test whether electroencephalography parameters, which are more sensitive and reliable markers, could predict the symptoms of acute mountain sickness. <h4>Methods</h4> Twenty-five participants were enrolled and separated into two groups to climb Mount Jade in Taiwan. We collected electrocardiography signals and arterial oxygen saturation data at ground, moderate (2,400 m), and high altitude (3,400 m). A spectral analysis of the electrocardiography was performed to assess the study subjects’ electroencephalography activity at different frequencies (α, β, θ, δ) and the mean power frequency of electrocardiography. The clinical symptoms and Lake Louise Acute Mountain Sickness scores of the subjects were recorded for comparison. <h4>Results</h4> A significant change in the δ power of electroencephalography was recorded in subjects ascending from the ground to a high altitude of 3,400 m in a 4-day itinerary. In addition, between the two groups of subjects with and without acute mountain sickness (Lake Louise Acute Mountain Sickness scores < 3 and ≥ 3), the δ power of electroencephalography at the fronto-parietal 1 and parietal 3 electrodes at moderate altitude as well as the changes of δ power and mean power frequency of electrocardiography over parietal 4 at high altitude showed a significant difference. At moderate altitude, the increasing δ power of electroencephalography at the parietal 4 electrode was related to the headache symptom of acute mountain sickness before ascending to high altitude. <h4>Conclusion</h4> At moderate altitude, the δ power increase of electroencephalography at the P4 electrode could be a predictor of acute mountain sickness symptoms before ascending to high altitude. Thus, electroencephalography had the potential to identify the risk of acute mountain sickness. |
| first_indexed | 2024-04-13T13:27:22Z |
| format | Article |
| id | doaj.art-ad3cd38603494939adc739353ca321c0 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-13T13:27:22Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-ad3cd38603494939adc739353ca321c02022-12-22T02:45:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-011711The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational studyKuo-Song ChangYu-Hui ChiuWei-Fong KaoCheryl C. H. YangChorng-Kuang HowYen-Kuang LinYuh-Shyan HwangDing-Kuo ChienMing-Kun HuangTerry B. J. Kuo<h4>Background</h4> The diagnosis of acute mountain sickness, which lacks a reliable and objective diagnostic tool, still depends on the clinical symptoms and signs and remains a major threat and unpredictable disease affecting millions of mountaineers. <h4>Objectives</h4> To record electroencephalography signals with small, convenient, wireless equipment and to test whether electroencephalography parameters, which are more sensitive and reliable markers, could predict the symptoms of acute mountain sickness. <h4>Methods</h4> Twenty-five participants were enrolled and separated into two groups to climb Mount Jade in Taiwan. We collected electrocardiography signals and arterial oxygen saturation data at ground, moderate (2,400 m), and high altitude (3,400 m). A spectral analysis of the electrocardiography was performed to assess the study subjects’ electroencephalography activity at different frequencies (α, β, θ, δ) and the mean power frequency of electrocardiography. The clinical symptoms and Lake Louise Acute Mountain Sickness scores of the subjects were recorded for comparison. <h4>Results</h4> A significant change in the δ power of electroencephalography was recorded in subjects ascending from the ground to a high altitude of 3,400 m in a 4-day itinerary. In addition, between the two groups of subjects with and without acute mountain sickness (Lake Louise Acute Mountain Sickness scores < 3 and ≥ 3), the δ power of electroencephalography at the fronto-parietal 1 and parietal 3 electrodes at moderate altitude as well as the changes of δ power and mean power frequency of electrocardiography over parietal 4 at high altitude showed a significant difference. At moderate altitude, the increasing δ power of electroencephalography at the parietal 4 electrode was related to the headache symptom of acute mountain sickness before ascending to high altitude. <h4>Conclusion</h4> At moderate altitude, the δ power increase of electroencephalography at the P4 electrode could be a predictor of acute mountain sickness symptoms before ascending to high altitude. Thus, electroencephalography had the potential to identify the risk of acute mountain sickness.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683632/?tool=EBI |
| spellingShingle | Kuo-Song Chang Yu-Hui Chiu Wei-Fong Kao Cheryl C. H. Yang Chorng-Kuang How Yen-Kuang Lin Yuh-Shyan Hwang Ding-Kuo Chien Ming-Kun Huang Terry B. J. Kuo The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study PLoS ONE |
| title | The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study |
| title_full | The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study |
| title_fullStr | The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study |
| title_full_unstemmed | The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study |
| title_short | The changes of electroencephalography in mountaineers on Mount Jade, Taiwan: An observational study |
| title_sort | changes of electroencephalography in mountaineers on mount jade taiwan an observational study |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9683632/?tool=EBI |
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