Multicenter Collaborative Study of the Interaction of Antifungal Combinations against <i>Candida</i> Spp. by Loewe Additivity and Bliss Independence-Based Response Surface Analysis

Multicenter Collaborative Study of the Interaction of Antifungal Combinations against <i>Candida</i> Spp. by Loewe Additivity and Bliss Independence-Based Response Surface Analysis

Combination antifungal therapy is widely used but not well understood. We analyzed the spectrophotometric readings from a multicenter study conducted by the New York State Department of Health to further characterize the in vitro interactions of the major classes of antifungal agents against <i&g...

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Bibliographic Details
Main Authors: Joseph Meletiadis, David R. Andes, Shawn R. Lockhart, Mahmoud A. Ghannoum, Cindy C. Knapp, Luis Ostrosky-Zeichner, Michael A. Pfaller, Vishnu Chaturvedi, Thomas J. Walsh
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Journal of Fungi
Subjects:
pharmacodynamic interactions
Loewe additivity
Bliss independence
synergy
antagonism
<i>Candida</i>
Online Access:https://www.mdpi.com/2309-608X/8/9/967

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https://www.mdpi.com/2309-608X/8/9/967

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