A case of Stevens-Johnson syndrome treated with oral cyclosporine
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin in...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3425;epage=3428;aulast=Griffith |
| _version_ | 1797232688398073856 |
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| author | Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik |
| author_facet | Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik |
| author_sort | Victoria Griffith |
| collection | DOAJ |
| description | Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respiratory infection, or other viral entities such as cocksackie A, roseola, or herpes simplex virus. We recommend initiating cyclosporine modified treatment, especially in children, upon any suspicion of SJS/TEN in a patient in order to halt the disease progression as early as possible. |
| first_indexed | 2024-04-24T16:04:15Z |
| format | Article |
| id | doaj.art-ad3de4c66ec742b89980d3d2a99d3094 |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-24T16:04:15Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-ad3de4c66ec742b89980d3d2a99d30942024-04-01T06:00:31ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632023-01-0112123425342810.4103/jfmpc.jfmpc_1162_23A case of Stevens-Johnson syndrome treated with oral cyclosporineVictoria GriffithAmanda RamnotSydney R ResnikBarry I ResnikStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) can occur at any age and are commonly caused by adverse drug events. Rapid diagnosis of SJS/TEN is imperative, followed by immediate cessation of offending agent and induction of appropriate treatment. Cyclosporine, a calcineurin inhibitor, has been reported to have a promising therapeutic effect in SJS/TEN patients with few side effects. Diagnosis of SJS/TEN in children is especially challenging as many of the symptoms mimic that of an upper respiratory infection, or other viral entities such as cocksackie A, roseola, or herpes simplex virus. We recommend initiating cyclosporine modified treatment, especially in children, upon any suspicion of SJS/TEN in a patient in order to halt the disease progression as early as possible.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3425;epage=3428;aulast=Griffithcyclosporine modifiedstevens-johnson syndrometoxic epidermal necrolysis |
| spellingShingle | Victoria Griffith Amanda Ramnot Sydney R Resnik Barry I Resnik A case of Stevens-Johnson syndrome treated with oral cyclosporine Journal of Family Medicine and Primary Care cyclosporine modified stevens-johnson syndrome toxic epidermal necrolysis |
| title | A case of Stevens-Johnson syndrome treated with oral cyclosporine |
| title_full | A case of Stevens-Johnson syndrome treated with oral cyclosporine |
| title_fullStr | A case of Stevens-Johnson syndrome treated with oral cyclosporine |
| title_full_unstemmed | A case of Stevens-Johnson syndrome treated with oral cyclosporine |
| title_short | A case of Stevens-Johnson syndrome treated with oral cyclosporine |
| title_sort | case of stevens johnson syndrome treated with oral cyclosporine |
| topic | cyclosporine modified stevens-johnson syndrome toxic epidermal necrolysis |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2023;volume=12;issue=12;spage=3425;epage=3428;aulast=Griffith |
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