Placental microRNAs in pregnancies with early onset intrauterine growth restriction and preeclampsia: potential impact on gene expression and pathophysiology

Placental microRNAs in pregnancies with early onset intrauterine growth restriction and preeclampsia: potential impact on gene expression and pathophysiology

Abstract Background A normally developed placenta is integral to a successful pregnancy. Preeclampsia (PE) and intrauterine growth restriction (IUGR) are two common pregnancy related complications that maybe a result of abnormal placental development. Placental microRNAs (miRNAs) have been investiga...

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Bibliographic Details
Main Authors: Zain Awamleh, Gregory B. Gloor, Victor K. M. Han
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Genomics
Subjects:
Intrauterine growth restriction
MicroRNA
Next-generation sequencing
Placenta
Preeclampsia
Online Access:http://link.springer.com/article/10.1186/s12920-019-0548-x

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