Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples
In this study, a novel material of core–shell structured magnetic molecularly imprinted polymers (Fe3O4@SiO2@Au (FSA)-MIPs) was successfully prepared for the rapid and selective determination of 4-methylmethcathinone (mephedrone, 4-MMC). The adsorption capacity of FSA-MIPs is 34.7 mg·g−1 at 308 K, w...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2022-05-01
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| Series: | e-Polymers |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/epoly-2022-0034 |
| _version_ | 1811203724951945216 |
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| author | Wu Fangsheng Zhang Zihua Liu Wei Liu Yuan Chen Xiujuan Liao Pingyong Han Qiaoying Song Lun Chen Hong Liu Wenbin |
| author_facet | Wu Fangsheng Zhang Zihua Liu Wei Liu Yuan Chen Xiujuan Liao Pingyong Han Qiaoying Song Lun Chen Hong Liu Wenbin |
| author_sort | Wu Fangsheng |
| collection | DOAJ |
| description | In this study, a novel material of core–shell structured magnetic molecularly imprinted polymers (Fe3O4@SiO2@Au (FSA)-MIPs) was successfully prepared for the rapid and selective determination of 4-methylmethcathinone (mephedrone, 4-MMC). The adsorption capacity of FSA-MIPs is 34.7 mg·g−1 at 308 K, which is significantly higher than magnetic non-imprinted polymers profiting from the imprinting effect. The FSA-MIPs have a short equilibrium (20 min) and could be reused more than six times. Moreover, the selectivity coefficients of FSA-MIPs for 4-MMC, 3,4-dimethylmethcathinone, butylone, 4-ethylmethcathinone, acetylfentanyl, and methylene blue are 4.01, 5.65, 7.62, 12.30, and 20.87 respectively, further indicating the markedly enhanced binding selectivity of FSA-MIPs. As an adsorbent, the FSA-MIPs were successfully applied for effective extraction of 4-MMC in three human urine samples with the recovery rates ranging from 85.5–92.6%. The results confirmed that the FSA-MIPs have good prospects in the extraction and separation of synthetic cathinones, which is suitable for further application in the criminal sciences field. |
| first_indexed | 2024-04-12T03:01:04Z |
| format | Article |
| id | doaj.art-ad435cddecfb4c2395fea73d621592bf |
| institution | Directory Open Access Journal |
| issn | 1618-7229 |
| language | English |
| last_indexed | 2024-04-12T03:01:04Z |
| publishDate | 2022-05-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | e-Polymers |
| spelling | doaj.art-ad435cddecfb4c2395fea73d621592bf2022-12-22T03:50:41ZengDe Gruytere-Polymers1618-72292022-05-0122148850410.1515/epoly-2022-0034Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samplesWu Fangsheng0Zhang Zihua1Liu Wei2Liu Yuan3Chen Xiujuan4Liao Pingyong5Han Qiaoying6Song Lun7Chen Hong8Liu Wenbin9Shanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaShanghai Key Laboratory of Crime Scene Evidence, Shanghai Research Institute of Criminal Science and Technology, 803 Zhongshan North 1st Road, Shanghai, 200083, ChinaIn this study, a novel material of core–shell structured magnetic molecularly imprinted polymers (Fe3O4@SiO2@Au (FSA)-MIPs) was successfully prepared for the rapid and selective determination of 4-methylmethcathinone (mephedrone, 4-MMC). The adsorption capacity of FSA-MIPs is 34.7 mg·g−1 at 308 K, which is significantly higher than magnetic non-imprinted polymers profiting from the imprinting effect. The FSA-MIPs have a short equilibrium (20 min) and could be reused more than six times. Moreover, the selectivity coefficients of FSA-MIPs for 4-MMC, 3,4-dimethylmethcathinone, butylone, 4-ethylmethcathinone, acetylfentanyl, and methylene blue are 4.01, 5.65, 7.62, 12.30, and 20.87 respectively, further indicating the markedly enhanced binding selectivity of FSA-MIPs. As an adsorbent, the FSA-MIPs were successfully applied for effective extraction of 4-MMC in three human urine samples with the recovery rates ranging from 85.5–92.6%. The results confirmed that the FSA-MIPs have good prospects in the extraction and separation of synthetic cathinones, which is suitable for further application in the criminal sciences field.https://doi.org/10.1515/epoly-2022-0034core–shellmagnetic molecularly imprinted polymers4-methylmethcathinoneextractionseparation |
| spellingShingle | Wu Fangsheng Zhang Zihua Liu Wei Liu Yuan Chen Xiujuan Liao Pingyong Han Qiaoying Song Lun Chen Hong Liu Wenbin Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples e-Polymers core–shell magnetic molecularly imprinted polymers 4-methylmethcathinone extraction separation |
| title | Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples |
| title_full | Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples |
| title_fullStr | Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples |
| title_full_unstemmed | Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples |
| title_short | Facile synthesis of core–shell structured magnetic Fe3O4@SiO2@Au molecularly imprinted polymers for high effective extraction and determination of 4-methylmethcathinone in human urine samples |
| title_sort | facile synthesis of core shell structured magnetic fe3o4 sio2 au molecularly imprinted polymers for high effective extraction and determination of 4 methylmethcathinone in human urine samples |
| topic | core–shell magnetic molecularly imprinted polymers 4-methylmethcathinone extraction separation |
| url | https://doi.org/10.1515/epoly-2022-0034 |
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