The Innate Cellular Immune Response in Xenotransplantation

The Innate Cellular Immune Response in Xenotransplantation

Xenotransplantation is very attractive strategy for addressing the shortage of donors. While hyper acute rejection (HAR) caused by natural antibodies and complement has been well defined, this is not the case for innate cellular xenogeneic rejection. An increasing body of evidence suggests that inna...

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Bibliographic Details
Main Authors: Akira Maeda, Shuhei Kogata, Chiyoshi Toyama, Pei-Chi Lo, Chizu Okamatsu, Riho Yamamoto, Kazunori Masahata, Masafumi Kamiyama, Hiroshi Eguchi, Masahito Watanabe, Hiroshi Nagashima, Hiroomi Okuyama, Shuji Miyagawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Immunology
Subjects:
xenotransplantation
macrophage-mediated xenogeneic rejection
innate cellular response
NETosis
ITIMs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.858604/full

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