Advanced Molecular Dynamics Approaches to Model a Tertiary Complex APRIL/TACI with Long Glycosaminoglycans
Glycosaminoglycans (GAGs) are linear anionic periodic polysaccharides participating in a number of biologically relevant processes in the extracellular matrix via interactions with their protein targets. Due to their periodicity, conformational flexibility, pseudo-symmetry of the sulfation pattern,...
Main Authors: | Mateusz Marcisz, Martyna Maszota-Zieleniak, Bertrand Huard, Sergey A. Samsonov |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/11/9/1349 |
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