N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis

N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis

Background/Aims This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA). Methods After RA synovial fibroblasts were stimulated by IL-17, the expression and production of...

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Bibliographic Details
Main Authors: Hae-Rim Kim, Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2019-01-01
Series:The Korean Journal of Internal Medicine
Subjects:
acetylcysteine
arthritis, rheumatoid
osteogenesis
rank ligand
interleukin-17
Online Access:http://www.kjim.org/upload/pdf/kjim-2016-329.pdf

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