Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice'
Abrams et al. report that a simple dietary supplement is sufficient to induce appendage regeneration in jellyfish, fruit flies, and mice (Abrams et al., 2021). This conclusion is surprising because it was previously thought that flies and mice lack the capacity for regeneration after injury. We repl...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
eLife Sciences Publications Ltd
2023-06-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/84435 |
| _version_ | 1797797553036591104 |
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| author | Anne Sustar John C Tuthill |
| author_facet | Anne Sustar John C Tuthill |
| author_sort | Anne Sustar |
| collection | DOAJ |
| description | Abrams et al. report that a simple dietary supplement is sufficient to induce appendage regeneration in jellyfish, fruit flies, and mice (Abrams et al., 2021). This conclusion is surprising because it was previously thought that flies and mice lack the capacity for regeneration after injury. We replicated the Drosophila experiments of Abrams et al. but did not observe any instances of leg regeneration. We also conclude that the "white blob" observed at the amputation site by Abrams et al. consists of bacteria and is not regenerated tissue. |
| first_indexed | 2024-03-13T03:50:04Z |
| format | Article |
| id | doaj.art-ad46aca8844e4994b40d578183b4ceee |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-03-13T03:50:04Z |
| publishDate | 2023-06-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-ad46aca8844e4994b40d578183b4ceee2023-06-22T15:37:53ZengeLife Sciences Publications LtdeLife2050-084X2023-06-011210.7554/eLife.84435Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice'Anne Sustar0https://orcid.org/0000-0002-9821-7456John C Tuthill1https://orcid.org/0000-0002-5689-5806Department of Physiology and Biophysics, University of Washington, Seattle, United StatesDepartment of Physiology and Biophysics, University of Washington, Seattle, United StatesAbrams et al. report that a simple dietary supplement is sufficient to induce appendage regeneration in jellyfish, fruit flies, and mice (Abrams et al., 2021). This conclusion is surprising because it was previously thought that flies and mice lack the capacity for regeneration after injury. We replicated the Drosophila experiments of Abrams et al. but did not observe any instances of leg regeneration. We also conclude that the "white blob" observed at the amputation site by Abrams et al. consists of bacteria and is not regenerated tissue.https://elifesciences.org/articles/84435regenerationlimbfruit fly |
| spellingShingle | Anne Sustar John C Tuthill Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' eLife regeneration limb fruit fly |
| title | Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' |
| title_full | Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' |
| title_fullStr | Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' |
| title_full_unstemmed | Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' |
| title_short | Comment on 'A conserved strategy for inducing appendage regeneration in moon jellyfish, Drosophila, and mice' |
| title_sort | comment on a conserved strategy for inducing appendage regeneration in moon jellyfish drosophila and mice |
| topic | regeneration limb fruit fly |
| url | https://elifesciences.org/articles/84435 |
| work_keys_str_mv | AT annesustar commentonaconservedstrategyforinducingappendageregenerationinmoonjellyfishdrosophilaandmice AT johnctuthill commentonaconservedstrategyforinducingappendageregenerationinmoonjellyfishdrosophilaandmice |