Malaria and COVID-19: unmasking their ties
Abstract The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this...
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| Format: | Article |
| Language: | English |
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BMC
2020-12-01
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| Series: | Malaria Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12936-020-03541-w |
| _version_ | 1818924771721609216 |
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| author | Mogahed Ismail Hassan Hussein Ahmed Abdalazim Dafallah Albashir Omer Ali Mohamed Ahmed Elawad Anmar Homeida |
| author_facet | Mogahed Ismail Hassan Hussein Ahmed Abdalazim Dafallah Albashir Omer Ali Mohamed Ahmed Elawad Anmar Homeida |
| author_sort | Mogahed Ismail Hassan Hussein |
| collection | DOAJ |
| description | Abstract The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this observation could be attributed to limited testing capacity, mitigation tools adopted and cultural habits, many theories have been postulated to explain this difference in prevalence and mortality. Because death tends to occur more in elders, both the role of demography, and how the age structure of a population may contribute to the difference in mortality rate between countries were discussed. The variable distribution of the ACEI/D and the ACE2 (C1173T substitution) polymorphisms has been postulated to explain this variable prevalence. Up-to-date data regarding the role of hydroxychloroquine (HCQ) and chloroquine (CQ) in COVID-19 have been summarized. The article also sheds lights on how the similarity of malaria and COVID-19 symptoms can lead to misdiagnosis of one disease for the other or overlooking the possibility of co-infection. As the COVID-19 pandemic threatens the delivery of malaria services, such as the distribution of insecticide-treated nets (ITNs), indoor residual spraying, as well as malaria chemoprevention there is an urgent need for rapid and effective responses to avoid malaria outbreaks. |
| first_indexed | 2024-12-20T02:30:38Z |
| format | Article |
| id | doaj.art-ad49b73a1bac47d19f9b43c3a6a0aa92 |
| institution | Directory Open Access Journal |
| issn | 1475-2875 |
| language | English |
| last_indexed | 2024-12-20T02:30:38Z |
| publishDate | 2020-12-01 |
| publisher | BMC |
| record_format | Article |
| series | Malaria Journal |
| spelling | doaj.art-ad49b73a1bac47d19f9b43c3a6a0aa922022-12-21T19:56:36ZengBMCMalaria Journal1475-28752020-12-0119111010.1186/s12936-020-03541-wMalaria and COVID-19: unmasking their tiesMogahed Ismail Hassan Hussein0Ahmed Abdalazim Dafallah Albashir1Omer Ali Mohamed Ahmed Elawad2Anmar Homeida3Faculty of Medicine, University of GeziraFaculty of Medicine, University of GeziraFaculty of Medicine, University of GeziraFaculty of Medicine, University of GeziraAbstract The incidence and mortality of COVID-19, according to the World Health Organization reports, shows a noticeable difference between North America, Western Europe, and South Asia on one hand and most African countries on the other hand, especially the malaria-endemic countries. Although this observation could be attributed to limited testing capacity, mitigation tools adopted and cultural habits, many theories have been postulated to explain this difference in prevalence and mortality. Because death tends to occur more in elders, both the role of demography, and how the age structure of a population may contribute to the difference in mortality rate between countries were discussed. The variable distribution of the ACEI/D and the ACE2 (C1173T substitution) polymorphisms has been postulated to explain this variable prevalence. Up-to-date data regarding the role of hydroxychloroquine (HCQ) and chloroquine (CQ) in COVID-19 have been summarized. The article also sheds lights on how the similarity of malaria and COVID-19 symptoms can lead to misdiagnosis of one disease for the other or overlooking the possibility of co-infection. As the COVID-19 pandemic threatens the delivery of malaria services, such as the distribution of insecticide-treated nets (ITNs), indoor residual spraying, as well as malaria chemoprevention there is an urgent need for rapid and effective responses to avoid malaria outbreaks.https://doi.org/10.1186/s12936-020-03541-wMalariaCOVID-19ACE2Hydroxychloroquine and chloroquineMalaria and COVID-19 syndemicsMalaria service |
| spellingShingle | Mogahed Ismail Hassan Hussein Ahmed Abdalazim Dafallah Albashir Omer Ali Mohamed Ahmed Elawad Anmar Homeida Malaria and COVID-19: unmasking their ties Malaria Journal Malaria COVID-19 ACE2 Hydroxychloroquine and chloroquine Malaria and COVID-19 syndemics Malaria service |
| title | Malaria and COVID-19: unmasking their ties |
| title_full | Malaria and COVID-19: unmasking their ties |
| title_fullStr | Malaria and COVID-19: unmasking their ties |
| title_full_unstemmed | Malaria and COVID-19: unmasking their ties |
| title_short | Malaria and COVID-19: unmasking their ties |
| title_sort | malaria and covid 19 unmasking their ties |
| topic | Malaria COVID-19 ACE2 Hydroxychloroquine and chloroquine Malaria and COVID-19 syndemics Malaria service |
| url | https://doi.org/10.1186/s12936-020-03541-w |
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