Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging

Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging

Background: Norbormide (NRB) is a selective rat toxicant endowed with vasoconstrictor activity confined to the rat peripheral arteries. In a recent work we used a fluorescent derivative of NRB (NRB-AF12), obtained by coupling the NBD fluorophore to the parent molecule via a linker, in order to gain...

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Bibliographic Details
Main Authors: Claudio D'Amore, Genny Orso, Alessia Forgiarini, Giulio Ceolotto, David Rennison, Giovanni Ribaudo, Morgan Jay-Smith, Brian Hopkins, Margaret A. Brimble, Sergio Bova
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Pharmacology
Subjects:
fluorescent probes
live cell imaging
norbormide
BODIPY
vascular smooth muscle cells
LX2 cells
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01055/full

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