Re-examining how complexin inhibits neurotransmitter release
Complexins play activating and inhibitory functions in neurotransmitter release. The complexin accessory helix inhibits release and was proposed to insert into SNARE complexes to prevent their full assembly. This model was supported by ‘superclamp’ and ‘poor-clamp’ mutations that enhanced or decreas...
Main Authors: | Thorsten Trimbuch, Junjie Xu, David Flaherty, Diana R Tomchick, Josep Rizo, Christian Rosenmund |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-05-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/02391 |
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