Alleviation of monocyte exhaustion by BCG derivative mycolic acid

Summary: Monocyte exhaustion with sustained pathogenic inflammation and immune-suppression, a hallmark of sepsis resulting from systemic infections, presents a challenge with limited therapeutic solutions. This study identified Methoxy-Mycolic Acid (M-MA), a branched mycolic acid derived from Mycoba...

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Bibliographic Details
Main Authors: Yajun Wu, Blake Caldwell, Jing Wang, Yao Zhang, Liwu Li
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224001998