Preclinical Evaluation of <sup>99m</sup>Tc-Labeled GRPR Antagonists maSSS/SES-PEG<sub>2</sub>-RM26 for Imaging of Prostate Cancer

Preclinical Evaluation of <sup>99m</sup>Tc-Labeled GRPR Antagonists maSSS/SES-PEG<sub>2</sub>-RM26 for Imaging of Prostate Cancer

Background: Gastrin-releasing peptide receptor (GRPR) is an important target for imaging of prostate cancer. The wide availability of single-photon emission computed tomography/computed tomography (SPECT/CT) and the generator-produced <sup>99m</sup>Tc can be utilized to facilitate the us...

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Bibliographic Details
Main Authors: Ayman Abouzayed, Sara S. Rinne, Hamideh Sabahnoo, Jens Sörensen, Vladimir Chernov, Vladimir Tolmachev, Anna Orlova
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pharmaceutics
Subjects:
prostate cancer
gastrin-releasing peptide receptor antagonist
technetium-99m
single-photon emission computed tomography
RM26
Online Access:https://www.mdpi.com/1999-4923/13/2/182

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